ID   VA5_LYCSI               Reviewed;         375 AA.
AC   A9QQ26;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=Venom allergen 5;
DE   AltName: Full=Antigen 5;
DE   Flags: Precursor;
OS   Lycosa singoriensis (Wolf spider) (Aranea singoriensis).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC   Araneomorphae; Entelegynae; Lycosoidea; Lycosidae; Lycosa.
OX   NCBI_TaxID=434756;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RA   Zhang Y., Liang S.;
RT   "Transcriptome analysis of the venom gland of the Chinese wolf spider
RT   Lycosa Singoriensis.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- PTM: Contains 9 disulfide bonds. {ECO:0000305}.
CC   -!- ALLERGEN: Causes an allergic reaction in human. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CRISP family. Venom allergen 5-like
CC       subfamily. {ECO:0000305}.
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DR   EMBL; EU247109; ABX75373.1; -; mRNA.
DR   AlphaFoldDB; A9QQ26; -.
DR   SMR; A9QQ26; -.
DR   ArachnoServer; AS000667; CRISP-1-Lycosa singoriensis.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.33.10; -; 1.
DR   InterPro; IPR014044; CAP_domain.
DR   InterPro; IPR035940; CAP_sf.
DR   InterPro; IPR001283; CRISP-related.
DR   InterPro; IPR002413; V5_allergen-like.
DR   PANTHER; PTHR10334; PTHR10334; 1.
DR   Pfam; PF00188; CAP; 1.
DR   PRINTS; PR00838; V5ALLERGEN.
DR   PRINTS; PR00837; V5TPXLIKE.
DR   SMART; SM00198; SCP; 1.
DR   SUPFAM; SSF55797; SSF55797; 1.
PE   2: Evidence at transcript level;
KW   Allergen; Disulfide bond; Glycoprotein; Secreted; Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..375
FT                   /note="Venom allergen 5"
FT                   /id="PRO_0000401917"
FT   DOMAIN          66..210
FT                   /note="SCP"
FT   CARBOHYD        300
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        366
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   375 AA;  42089 MW;  75E3611120DFD432 CRC64;
     MSAPVGIPSL LLALCALLCV LNAVRSAYCP DPYKRYSDQH SYCVGVCCSC AKYRRGVSPW
     LKKELVRLHN NLRSKVAGGK SHSVDHLPRA TNMLEMVWDD ELAEVAQRWS DKCERKSDCE
     DCRRVGRFGV GQIIFEFDGK MDGKDMENEF FSRFMALQSF RKEQVARFTA GTNPKTAQIL
     WAKTWRIGCG FLDFNYPGNG RRYTQIVCNY GPKGNEEGEE VYKAGSVCSS CPANTCCGDA
     CKKHNLKANY HGLCKVIDEN LPPEGNVPHK KTGNEVFYCG FNDESDCRHT VEGVDRWIRN
     VTTGGTWLNT YLGNYGHTVI EVRSAHHLQV RQAMPGHQDP QWTHGGRTTL SVPAVRGFGG
     GRQILNLTHL PPCRR