ID   VA5_TITSE               Reviewed;         212 AA.
AC   P85840;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Venom allergen 5;
DE   AltName: Full=Antigen 5;
DE   AltName: Full=Cysteine-rich venom protein;
DE            Short=CRVP;
DE   Flags: Fragments;
OS   Tityus serrulatus (Brazilian scorpion).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Scorpiones; Buthida; Buthoidea; Buthidae; Tityus.
OX   NCBI_TaxID=6887;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RC   TISSUE=Venom {ECO:0000269|Ref.1};
RA   Richardson M., Borges M.H., Cordeiro M.N., Pimenta A.M.C., de Lima M.E.,
RA   Rates B.;
RT   "Allergenic protein from venom of Brazilian scorpion Tityus serrulatus.";
RL   Submitted (MAY-2008) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000269|Ref.1}.
CC   -!- PTM: Contains disulfide bonds. {ECO:0000250|UniProtKB:P10736}.
CC   -!- ALLERGEN: Causes an allergic reaction in human.
CC       {ECO:0000250|UniProtKB:P10736}.
CC   -!- SIMILARITY: Belongs to the CRISP family. Venom allergen 5-like
CC       subfamily. {ECO:0000305}.
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DR   AlphaFoldDB; P85840; -.
DR   SMR; P85840; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.33.10; -; 2.
DR   InterPro; IPR018244; Allrgn_V5/Tpx1_CS.
DR   InterPro; IPR014044; CAP_domain.
DR   InterPro; IPR035940; CAP_sf.
DR   InterPro; IPR001283; CRISP-related.
DR   PANTHER; PTHR10334; PTHR10334; 1.
DR   Pfam; PF00188; CAP; 1.
DR   PRINTS; PR00837; V5TPXLIKE.
DR   SMART; SM00198; SCP; 1.
DR   SUPFAM; SSF55797; SSF55797; 1.
DR   PROSITE; PS01010; CRISP_2; 1.
PE   1: Evidence at protein level;
KW   Allergen; Direct protein sequencing; Disulfide bond; Secreted.
FT   CHAIN           1..>212
FT                   /note="Venom allergen 5"
FT                   /id="PRO_0000343458"
FT   DOMAIN          40..104
FT                   /note="SCP"
FT   NON_CONS        120..121
FT                   /evidence="ECO:0000303|Ref.1"
FT   NON_TER         212
FT                   /evidence="ECO:0000303|Ref.1"
SQ   SEQUENCE   212 AA;  24047 MW;  C6A68EF0110A0F42 CRC64;
     ECPALYRRYS KEHTFCKTKN QKCNIKRWGV SQDDRNTIIN LHNKVRNNIA LGQDQSGRLP
     AAGDMLEMEW DDELAQIAQK LADQCVFKHD CDDCRKVENF DVGQNIFTRG ITAVEIPDPF
     KSWTQLYVCN YGPAGNLDDS ELYKVDKPCE KCPSNTCCGS HCKKHNKSTS YLGLCDVLNG
     SGPDFDETDF SNYIFNCDFK PESDCNNKVE GS