ID   VAB2_CANGA              Reviewed;         290 AA.
AC   Q6FLL9;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit VAB2;
DE            Short=BLOC-1 subunit VAB2;
GN   Name=VAB2; OrderedLocusNames=CAGL0L02409g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC       complex-1 (BLOC-1) involved in endosomal cargo sorting. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC       complex-1 (BLOC-1) composed of at least BLI1, BLS1, CNL1, KXD1, SNN1
CC       and VAB2. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle {ECO:0000250}. Vacuole
CC       {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the VAB2 family. {ECO:0000305}.
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DR   EMBL; CR380958; CAG61845.1; -; Genomic_DNA.
DR   RefSeq; XP_448875.1; XM_448875.1.
DR   AlphaFoldDB; Q6FLL9; -.
DR   SMR; Q6FLL9; -.
DR   STRING; 5478.XP_448875.1; -.
DR   EnsemblFungi; CAG61845; CAG61845; CAGL0L02409g.
DR   GeneID; 2890905; -.
DR   KEGG; cgr:CAGL0L02409g; -.
DR   CGD; CAL0135586; CAGL0L02409g.
DR   VEuPathDB; FungiDB:CAGL0L02409g; -.
DR   eggNOG; ENOG502S95F; Eukaryota.
DR   HOGENOM; CLU_959745_0_0_1; -.
DR   InParanoid; Q6FLL9; -.
DR   OMA; HICITEP; -.
DR   Proteomes; UP000002428; Chromosome L.
DR   GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR   GO; GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Cytoplasmic vesicle; Reference proteome; Transport;
KW   Vacuole.
FT   CHAIN           1..290
FT                   /note="Biogenesis of lysosome-related organelles complex 1
FT                   subunit VAB2"
FT                   /id="PRO_0000320512"
FT   REGION          173..211
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          54..130
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   290 AA;  32798 MW;  E0B112EBE9B8138B CRC64;
     MDNKPLITVA EASEYKELLA LEKLPQSSQL SYKAIFKSVS SEWEQVKTDI THVNENILKD
     INEEIEQTDQ IEKKLKSSFK SINQHYHKLL KHRRNRQNDE GTSDLFLKYK NDVNELASNI
     ETIENGLDMV IQNMISFDST SSLDGDSLFN SSIITKRHYP LLYDLIHKNY NKGQNSDKTS
     KDNSKITTDV TLPASDEDNS PDIEEQQSKL SSLSFSIEKA QNPIPVDKAK NTDNSSRSII
     NSNVKIKNPT LILPMIKQRA QPSVALDAKP VIARDSYKAD TKSIIAPEIT