ID   VAB2_YEAS7              Reviewed;         282 AA.
AC   A6ZQU2;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit VAB2;
DE            Short=BLOC-1 subunit VAB2;
DE   AltName: Full=VAC8-binding protein 2;
GN   Name=VAB2; ORFNames=SCY_1489;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA   Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA   Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT   strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC       complex-1 (BLOC-1) involved in endosomal cargo sorting. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC       complex-1 (BLOC-1) composed of at least BLI1, BLS1, CNL1, KXD1, SNN1
CC       and VAB2. Interacts with VAC8. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle {ECO:0000250}. Vacuole
CC       {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the VAB2 family. {ECO:0000305}.
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DR   EMBL; AAFW02000048; EDN62962.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6ZQU2; -.
DR   SMR; A6ZQU2; -.
DR   EnsemblFungi; EDN62962; EDN62962; SCY_1489.
DR   HOGENOM; CLU_086126_0_0_1; -.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR   GO; GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Cytoplasmic vesicle; Transport; Vacuole.
FT   CHAIN           1..282
FT                   /note="Biogenesis of lysosome-related organelles complex 1
FT                   subunit VAB2"
FT                   /id="PRO_0000320515"
FT   COILED          64..140
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   282 AA;  31365 MW;  8F7CA122F91E491A CRC64;
     MVADLTKGIL KWKSRIEFDA VGSSSYYEEL KGLPPLASHK KLTQAAIFNS TKYELLQVKK
     DILSIYEVVS RDIDEERNQM QQIELQLKKS LKKVEHSYKN VLKQRASTNC INGNDRLLAN
     AEKKIGSLNE ELACVNDIVS DIVNNLTALN ANLPKKAQLL KDDSINVAHY PLLFDFLHKS
     CPKSIIATSE ASIHENASPS PLLEHDELPA ESINSFYGEN ELQSDSLAPL QTHDDNISSC
     KKILPPKFNT TSGPSIETNF ENISADGLTY TKCSLKNSIS LT