ID   VACHT_MACFU             Reviewed;          66 AA.
AC   Q28487;
DT   19-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Vesicular acetylcholine transporter;
DE            Short=VAChT;
DE   AltName: Full=Solute carrier family 18 member 3;
DE   Flags: Fragment;
GN   Name=SLC18A3;
OS   Macaca fuscata fuscata (Japanese macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9543;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Blood;
RX   PubMed=9073174; DOI=10.1016/s0169-328x(96)00231-8;
RA   Misawa H., Matsuura J., Oda Y., Takahashi R., Deguchi T.;
RT   "Human choline acetyltransferase mRNAs with different 5'-region produce a
RT   69-kDa major translation product.";
RL   Brain Res. Mol. Brain Res. 44:323-333(1997).
CC   -!- FUNCTION: Involved in acetylcholine transport into synaptic vesicles.
CC       {ECO:0000250|UniProtKB:Q16572}.
CC   -!- SUBUNIT: Interacts with SEC14L1. {ECO:0000250|UniProtKB:O35304}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Vesicular
CC       transporter family. {ECO:0000305}.
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DR   EMBL; D83487; BAA11930.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q28487; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Membrane; Neurotransmitter transport; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           <1..>66
FT                   /note="Vesicular acetylcholine transporter"
FT                   /id="PRO_0000127518"
FT   TRANSMEM        <1..15
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        16..>66
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          43..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT   NON_TER         66
SQ   SEQUENCE   66 AA;  7254 MW;  D8CF378C482C9CE5 CRC64;
     GMGLANLLYA PVLLLLRNVG LLTRSRSERD VLLDEPPQGL YDAVRLRERP VSGQDGEPRS
     PPGPFD