VAP41_ARATH
ID VAP41_ARATH Reviewed; 266 AA.
AC Q1ECE0; P93040; Q56YB2; Q9LVV9;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2006, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=Vesicle-associated protein 4-1;
DE AltName: Full=Plant VAP homolog 4-1;
DE Short=AtPVA41;
DE AltName: Full=Protein MEMBRANE-ASSOCIATED MANNITOL-INDUCED;
DE Short=AtMAMI;
DE AltName: Full=VAMP-associated protein 4-1;
GN Name=PVA41; Synonyms=MAMI; OrderedLocusNames=At5g54110; ORFNames=MJP23.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND INDUCTION.
RX PubMed=9300811; DOI=10.1016/s0167-4838(97)00063-0;
RA Galaud J.P., Laval V., Carriere M., Barre A., Canut H., Rouge P.,
RA Pont-Lezica R.;
RT "Osmotic stress activated expression of an Arabidopsis plasma membrane-
RT associated protein: sequence and predicted secondary structure.";
RL Biochim. Biophys. Acta 1341:79-86(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Quinitio C., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-233.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play a role in vesicle trafficking. {ECO:0000250}.
CC -!- INDUCTION: By treatment with mannitol. {ECO:0000269|PubMed:9300811}.
CC -!- SIMILARITY: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17)
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB41326.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=BAA97133.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U83655; AAB41326.1; ALT_FRAME; mRNA.
DR EMBL; AB018115; BAA97133.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED96452.1; -; Genomic_DNA.
DR EMBL; BT025794; ABF83684.1; -; mRNA.
DR EMBL; AK221411; BAD94385.1; -; mRNA.
DR RefSeq; NP_568804.1; NM_124791.3.
DR AlphaFoldDB; Q1ECE0; -.
DR SMR; Q1ECE0; -.
DR BioGRID; 20742; 3.
DR IntAct; Q1ECE0; 3.
DR STRING; 3702.AT5G54110.1; -.
DR iPTMnet; Q1ECE0; -.
DR SwissPalm; Q1ECE0; -.
DR PaxDb; Q1ECE0; -.
DR PRIDE; Q1ECE0; -.
DR ProteomicsDB; 242314; -.
DR EnsemblPlants; AT5G54110.1; AT5G54110.1; AT5G54110.
DR GeneID; 835498; -.
DR Gramene; AT5G54110.1; AT5G54110.1; AT5G54110.
DR KEGG; ath:AT5G54110; -.
DR Araport; AT5G54110; -.
DR TAIR; locus:2166582; AT5G54110.
DR eggNOG; KOG0439; Eukaryota.
DR HOGENOM; CLU_067947_0_0_1; -.
DR InParanoid; Q1ECE0; -.
DR OMA; FFLYEPG; -.
DR OrthoDB; 1263580at2759; -.
DR PhylomeDB; Q1ECE0; -.
DR PRO; PR:Q1ECE0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q1ECE0; baseline and differential.
DR Genevisible; Q1ECE0; AT.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR GO; GO:0009536; C:plastid; HDA:TAIR.
DR GO; GO:0090158; P:endoplasmic reticulum membrane organization; IBA:GO_Central.
DR GO; GO:0061817; P:endoplasmic reticulum-plasma membrane tethering; IBA:GO_Central.
DR GO; GO:0006970; P:response to osmotic stress; IEP:TAIR.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR000535; MSP_dom.
DR InterPro; IPR008962; PapD-like_sf.
DR InterPro; IPR016763; VAP.
DR PANTHER; PTHR10809; PTHR10809; 1.
DR Pfam; PF00635; Motile_Sperm; 1.
DR SUPFAM; SSF49354; SSF49354; 1.
DR PROSITE; PS50202; MSP; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Phosphoprotein; Reference proteome.
FT CHAIN 1..266
FT /note="Vesicle-associated protein 4-1"
FT /id="PRO_0000402176"
FT DOMAIN 76..199
FT /note="MSP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00132"
FT REGION 28..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 219..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 200..228
FT /evidence="ECO:0000255"
FT MOD_RES 264
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8VYN2"
FT CONFLICT 80
FT /note="D -> G (in Ref. 5; BAD94385)"
FT /evidence="ECO:0000305"
FT CONFLICT 141
FT /note="F -> L (in Ref. 5; BAD94385)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 266 AA; 30255 MW; 9532ADB6303FE571 CRC64;
MPIGDRQNPS VEKKKNLFRL CPFWQRRSTT SSSSTQNPNQ NYRSRHGNRN TDISAVSKPP
LTMSSVARSL LPARRRLRLD PSSYLYFPYE PGKQVRSAIK LKNTSKSHTA FKFQTTAPKS
CYMRPPGGVL APGESVFATV FKFVEHPENN EKQPLNQKSK VKFKIMSLKV KPGVEYVPEL
FDEQKDQVAV EQVLRVIFID ADRPSAALEK LKRQLDEAEA AVEARKKPPP ETGPRVVGEG
LVIDEWKERR EKYLARQQVE SVDSLS
