ID   VAPB1_RICFE             Reviewed;         103 AA.
AC   Q4UMA9;
DT   04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Antitoxin VapB1;
GN   Name=vapB1; OrderedLocusNames=RF_0457;
OS   Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=315456;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1525 / URRWXCal2;
RX   PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA   Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E.,
RA   Parinello H., Claverie J.-M., Raoult D.;
RT   "The genome sequence of Rickettsia felis identifies the first putative
RT   conjugative plasmid in an obligate intracellular parasite.";
RL   PLoS Biol. 3:1-12(2005).
RN   [2]
RP   FUNCTION, AND EXPRESSION IN E.COLI.
RC   STRAIN=ATCC VR-1525 / URRWXCal2;
RX   PubMed=22046301; DOI=10.1371/journal.pone.0026528;
RA   Audoly G., Vincentelli R., Edouard S., Georgiades K., Mediannikov O.,
RA   Gimenez G., Socolovschi C., Mege J.L., Cambillau C., Raoult D.;
RT   "Effect of rickettsial toxin VapC on its eukaryotic host.";
RL   PLoS ONE 6:E26528-E26528(2011).
CC   -!- FUNCTION: Antitoxin component of a type II toxin-antitoxin (TA) system.
CC       Upon expression in E.coli neutralizes the effect of cognate toxin
CC       VapC1, partially inhibits the RNase activity of VapC1 in vitro.
CC       {ECO:0000269|PubMed:22046301}.
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DR   EMBL; CP000053; AAY61308.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q4UMA9; -.
DR   STRING; 315456.RF_0457; -.
DR   EnsemblBacteria; AAY61308; AAY61308; RF_0457.
DR   KEGG; rfe:RF_0457; -.
DR   HOGENOM; CLU_2384284_0_0_5; -.
DR   OMA; RNTKQDI; -.
DR   Proteomes; UP000008548; Chromosome.
PE   4: Predicted;
KW   Toxin-antitoxin system.
FT   CHAIN           1..103
FT                   /note="Antitoxin VapB1"
FT                   /id="PRO_0000432239"
SQ   SEQUENCE   103 AA;  12156 MW;  AB66EA6870B2CABE CRC64;
     MQLFLRINMA QIIRATEFVR SFSDIMNRVY YKGESFDVQK GNHIVARITP AETKPSIAVR
     DLEEAFKNGP HLDPEDADQF MKDIEEIRRS TRQDIKKLVE RWD