ID   VAPB4_MYCTO             Reviewed;          85 AA.
AC   P9WF20; L0T456; O07782; Q7D9K5;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Antitoxin VapB4;
DE   AltName: Full=VapB-mt4;
GN   Name=vapB4; OrderedLocusNames=MT0626;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Antitoxin component of a type II toxin-antitoxin (TA) system.
CC       Antitoxin that counteracts the effect of the VapC4 toxin (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with cognate toxin VapC4. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phD/YefM antitoxin family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK44850.1; -; Genomic_DNA.
DR   PIR; G70908; G70908.
DR   RefSeq; WP_003403125.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WF20; -.
DR   SMR; P9WF20; -.
DR   EnsemblBacteria; AAK44850; AAK44850; MT0626.
DR   GeneID; 45424564; -.
DR   KEGG; mtc:MT0626; -.
DR   PATRIC; fig|83331.31.peg.658; -.
DR   HOGENOM; CLU_174702_2_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   InterPro; IPR006442; Antitoxin_Phd/YefM.
DR   InterPro; IPR036165; YefM-like_sf.
DR   Pfam; PF02604; PhdYeFM_antitox; 1.
DR   SUPFAM; SSF143120; SSF143120; 1.
PE   3: Inferred from homology;
KW   Toxin-antitoxin system.
FT   CHAIN           1..85
FT                   /note="Antitoxin VapB4"
FT                   /id="PRO_0000428615"
SQ   SEQUENCE   85 AA;  9681 MW;  3410851F93D4EACE CRC64;
     MSATIPARDL RNHTAEVLRR VAAGEEIEVL KDNRPVARIV PLKRRRQWLP AAEVIGELVR
     LGPDTTNLGE ELRETLTQTT DDVRW