ID   VAPB6_MYCTU             Reviewed;          51 AA.
AC   P9WJ57; L0T4C5; O06782; Q7D9H1;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 27.
DE   RecName: Full=Putative antitoxin VapB6;
GN   Name=vapB6; OrderedLocusNames=Rv0657c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   POSSIBLE FUNCTION.
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=15718296; DOI=10.1093/nar/gki201;
RA   Pandey D.P., Gerdes K.;
RT   "Toxin-antitoxin loci are highly abundant in free-living but lost from
RT   host-associated prokaryotes.";
RL   Nucleic Acids Res. 33:966-976(2005).
CC   -!- FUNCTION: Antitoxin component of a possible type II toxin-antitoxin
CC       (TA) system. The cognate toxin is VapC6. {ECO:0000305|PubMed:15718296}.
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DR   EMBL; AL123456; CCP43400.1; -; Genomic_DNA.
DR   PIR; D70534; D70534.
DR   RefSeq; NP_215171.1; NC_000962.3.
DR   RefSeq; WP_003403368.1; NZ_NVQJ01000007.1.
DR   AlphaFoldDB; P9WJ57; -.
DR   SMR; P9WJ57; -.
DR   STRING; 83332.Rv0657c; -.
DR   PaxDb; P9WJ57; -.
DR   DNASU; 888077; -.
DR   GeneID; 888077; -.
DR   KEGG; mtu:Rv0657c; -.
DR   TubercuList; Rv0657c; -.
DR   eggNOG; COG5450; Bacteria.
DR   OMA; MGATTKK; -.
DR   Proteomes; UP000001584; Chromosome.
DR   InterPro; IPR019239; VapB_antitoxin.
DR   Pfam; PF09957; VapB_antitoxin; 1.
PE   4: Predicted;
KW   Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..51
FT                   /note="Putative antitoxin VapB6"
FT                   /id="PRO_0000408054"
SQ   SEQUENCE   51 AA;  5905 MW;  5480968ED5001858 CRC64;
     MSVTQIDLDD EALADVMRIA AVHTKKEAVN LAMRDYVERF RRIEALARSR E