VAPB7_ARCFU
ID VAPB7_ARCFU Reviewed; 65 AA.
AC O29926;
DT 20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 20-JUN-2001, sequence version 2.
DT 25-MAY-2022, entry version 85.
DE RecName: Full=Putative antitoxin VapB7;
GN Name=vapB7; OrderedLocusNames=AF_0319;
OS Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS 100126 / VC-16).
OC Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC Archaeoglobus.
OX NCBI_TaxID=224325;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX PubMed=9389475; DOI=10.1038/37052;
RA Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA Smith H.O., Woese C.R., Venter J.C.;
RT "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT archaeon Archaeoglobus fulgidus.";
RL Nature 390:364-370(1997).
RN [2]
RP IDENTIFICATION, AND POSSIBLE FUNCTION.
RC STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX PubMed=15718296; DOI=10.1093/nar/gki201;
RA Pandey D.P., Gerdes K.;
RT "Toxin-antitoxin loci are highly abundant in free-living but lost from
RT host-associated prokaryotes.";
RL Nucleic Acids Res. 33:966-976(2005).
CC -!- FUNCTION: Possibly the antitoxin component of a type II toxin-antitoxin
CC (TA) system. Its cognate toxin is VapC7 (Potential). {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the UPF0165 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB90924.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AE000782; AAB90924.1; ALT_INIT; Genomic_DNA.
DR PIR; G69289; G69289.
DR RefSeq; WP_048064614.1; NC_000917.1.
DR AlphaFoldDB; O29926; -.
DR SMR; O29926; -.
DR STRING; 224325.AF_0319; -.
DR EnsemblBacteria; AAB90924; AAB90924; AF_0319.
DR GeneID; 24793857; -.
DR KEGG; afu:AF_0319; -.
DR eggNOG; arCOG03880; Archaea.
DR HOGENOM; CLU_200885_3_1_2; -.
DR Proteomes; UP000002199; Chromosome.
DR Gene3D; 4.10.1150.10; -; 1.
DR InterPro; IPR008203; AF2212-like.
DR InterPro; IPR024069; AF2212-like_dom_sf.
DR Pfam; PF01954; DUF104; 1.
PE 3: Inferred from homology;
KW Reference proteome; Toxin-antitoxin system.
FT CHAIN 1..65
FT /note="Putative antitoxin VapB7"
FT /id="PRO_0000156848"
SQ SEQUENCE 65 AA; 7341 MW; 888785E3494AE3A4 CRC64;
MPKVIEAVYE NGVFKPLQKV DLKEGEKVKV ELKESVVESV AGILKVSDEK VKKALEMIEY
GEDIY