ID   VAPD_AGGAC              Reviewed;          95 AA.
AC   Q52243;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 43.
DE   RecName: Full=Endoribonuclease VapD homolog;
DE            EC=3.1.-.-;
DE   AltName: Full=Virulence-associated protein D homolog;
OS   Aggregatibacter actinomycetemcomitans (Actinobacillus
OS   actinomycetemcomitans) (Haemophilus actinomycetemcomitans).
OG   Plasmid pVT736-1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Aggregatibacter.
OX   NCBI_TaxID=714;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7543479; DOI=10.1128/jb.177.15.4474-4480.1995;
RA   Galli D.M., Leblanc D.J.;
RT   "Transcriptional analysis of rolling circle replicating plasmid pVT736-1:
RT   evidence for replication control by antisense RNA.";
RL   J. Bacteriol. 177:4474-4480(1995).
CC   -!- FUNCTION: Cleaves ssRNA, mostly between U:A. {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the VapD ribonuclease family. {ECO:0000305}.
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DR   EMBL; L24000; AAC37126.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q52243; -.
DR   SMR; Q52243; -.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   InterPro; IPR016368; VapD.
DR   InterPro; IPR019199; Virulence_VapD/CRISPR_Cas2.
DR   Pfam; PF09827; CRISPR_Cas2; 1.
DR   PIRSF; PIRSF002882; VapD; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Nuclease; Plasmid; Virulence.
FT   CHAIN           1..95
FT                   /note="Endoribonuclease VapD homolog"
FT                   /id="PRO_0000217269"
SQ   SEQUENCE   95 AA;  11190 MW;  3424348E815BF62A CRC64;
     MYAIAFDLEI SELKKHYGDP YNNAYFEVKS ELEKIGFEWT QGSVYLSKDP RNNLATVYKA
     INLLSNIDWF KHSVRDIRAF KVEDWSDFTE IVKTS