ID   VAPD_DICNO              Reviewed;          93 AA.
AC   Q46565; Q46556; Q46566; Q46570; Q46572;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Endoribonuclease VapD;
DE            EC=3.1.-.-;
DE   AltName: Full=Virulence-associated protein D;
GN   Name=vapD;
OS   Dichelobacter nodosus (Bacteroides nodosus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Cardiobacteriales;
OC   Cardiobacteriaceae; Dichelobacter.
OX   NCBI_TaxID=870;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=A198;
RX   PubMed=1748867; DOI=10.1099/00221287-137-9-2117;
RA   Katz M.E., Howarth P.M., Yong W.K., Riffkin G.G., Depiazzi L.J., Rood J.I.;
RT   "Identification of three gene regions associated with virulence in
RT   Dichelobacter nodosus, the causative agent of ovine footrot.";
RL   J. Gen. Microbiol. 137:2117-2124(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=A198;
RX   PubMed=1398971; DOI=10.1128/iai.60.11.4586-4592.1992;
RA   Katz M.E., Rood J.I., Strugnell R.A.;
RT   "Molecular characterization of a genomic region associated with virulence
RT   in Dichelobacter nodosus.";
RL   Infect. Immun. 60:4586-4592(1992).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=A198;
RX   PubMed=8169216; DOI=10.1128/jb.176.9.2663-2669.1994;
RA   Katz M.E., Wright C.L., Gartside T.S., Cheetham B.F., Doidge C.V.,
RA   Moses E.K., Rood J.I.;
RT   "Genetic organization of the duplicated vap region of the Dichelobacter
RT   nodosus genome.";
RL   J. Bacteriol. 176:2663-2669(1994).
CC   -!- FUNCTION: Cleaves ssRNA, mostly between U:A. {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the VapD ribonuclease family. {ECO:0000305}.
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DR   EMBL; L31763; AAB00950.1; -; Genomic_DNA.
DR   EMBL; L31763; AAB00940.1; -; Genomic_DNA.
DR   EMBL; L22308; AAA20204.1; -; Unassigned_DNA.
DR   EMBL; L22307; AAA20123.1; -; Unassigned_DNA.
DR   EMBL; M74565; AAA23348.1; -; Genomic_DNA.
DR   PIR; A49205; A49205.
DR   RefSeq; WP_012030611.1; NZ_SRJB01000012.1.
DR   AlphaFoldDB; Q46565; -.
DR   SMR; Q46565; -.
DR   PATRIC; fig|870.4.peg.1264; -.
DR   OMA; NMNEDMA; -.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   InterPro; IPR016368; VapD.
DR   InterPro; IPR019199; Virulence_VapD/CRISPR_Cas2.
DR   Pfam; PF09827; CRISPR_Cas2; 1.
DR   PIRSF; PIRSF002882; VapD; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Nuclease; Virulence.
FT   CHAIN           1..93
FT                   /note="Endoribonuclease VapD"
FT                   /id="PRO_0000217270"
SQ   SEQUENCE   93 AA;  10590 MW;  15112582A678D9B0 CRC64;
     MYAIAFDLEI AELKKHYGEP YNGAYLEIGK ELKAIGFEWT QGSVYLSNDN NLATVYRAIS
     TLSKIDWFKS SVRDIRAFKV EDWSDFTAIV KGA