位置:首页 > 蛋白库 > VAPD_HAEIN
VAPD_HAEIN
ID   VAPD_HAEIN              Reviewed;          91 AA.
AC   P71351;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Endoribonuclease VapD;
DE            EC=3.1.-.-;
DE   AltName: Full=Virulence-associated protein D;
GN   Name=vapD; OrderedLocusNames=HI_0450;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
RN   [2]
RP   PROTEIN SEQUENCE OF 76-80.
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=10675023;
RX   DOI=10.1002/(sici)1522-2683(20000101)21:2<411::aid-elps411>3.0.co;2-4;
RA   Langen H., Takacs B., Evers S., Berndt P., Lahm H.W., Wipf B., Gray C.,
RA   Fountoulakis M.;
RT   "Two-dimensional map of the proteome of Haemophilus influenzae.";
RL   Electrophoresis 21:411-429(2000).
CC   -!- FUNCTION: Cleaves ssRNA, mostly between U:A. {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the VapD ribonuclease family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L42023; AAC22108.1; -; Genomic_DNA.
DR   PIR; C64069; C64069.
DR   RefSeq; NP_438611.1; NC_000907.1.
DR   RefSeq; WP_005693712.1; NC_000907.1.
DR   AlphaFoldDB; P71351; -.
DR   SMR; P71351; -.
DR   STRING; 71421.HI_0450; -.
DR   EnsemblBacteria; AAC22108; AAC22108; HI_0450.
DR   KEGG; hin:HI_0450; -.
DR   PATRIC; fig|71421.8.peg.470; -.
DR   eggNOG; COG3309; Bacteria.
DR   HOGENOM; CLU_145265_4_0_6; -.
DR   OMA; NMNEDMA; -.
DR   BioCyc; HINF71421:G1GJ1-466-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   InterPro; IPR016368; VapD.
DR   InterPro; IPR019199; Virulence_VapD/CRISPR_Cas2.
DR   Pfam; PF09827; CRISPR_Cas2; 1.
DR   PIRSF; PIRSF002882; VapD; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Hydrolase; Nuclease; Reference proteome;
KW   Virulence.
FT   CHAIN           1..91
FT                   /note="Endoribonuclease VapD"
FT                   /id="PRO_0000217271"
SQ   SEQUENCE   91 AA;  10543 MW;  70B23CDE28E083E7 CRC64;
     MYAIAFLVVK DTQDYHPKGV QQAYTDIGAV LAKFGFVRTQ GSLYINMNED MANLFQAMNA
     LKQLAWISQS VRDIRAFRIE QWSDFTDFIR N
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024