ID   VAP_CAMVC               Reviewed;         129 AA.
AC   P03552;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1988, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Virion-associated protein;
DE            Short=Vap;
DE   AltName: Full=Protein 3;
DE            Short=P3;
GN   ORFNames=ORF III;
OS   Cauliflower mosaic virus (strain CM-1841) (CaMV).
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Caulimoviridae; Caulimovirus.
OX   NCBI_TaxID=10644;
OH   NCBI_TaxID=3702; Arabidopsis thaliana (Mouse-ear cress).
OH   NCBI_TaxID=3705; Brassica.
OH   NCBI_TaxID=3725; Raphanus.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6269062; DOI=10.1093/nar/9.12.2871;
RA   Gardner R.C., Howarth A.J., Hahn P., Brown-Luedi M., Shepherd R.J.,
RA   Messing J.;
RT   "The complete nucleotide sequence of an infectious clone of cauliflower
RT   mosaic virus by M13mp7 shotgun sequencing.";
RL   Nucleic Acids Res. 9:2871-2888(1981).
CC   -!- FUNCTION: Plays a role in virus cell-to-cell and plant-to-plant
CC       transmission. Interacts with virion icosahedral capsid and movement
CC       protein, thereby facilitating virion cell-to-cell transmission through
CC       plasmodesmata opened by viral movement protein. Also interacts with
CC       aphid transmission factor, attaching the virion to aphid stylet when
CC       the animal feeds on an virus infected plant. Aphid saliva may later
CC       detach the virion, inducing release of infectious particles when the
CC       animal feeds on a new plant (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homotetramer, through coiled-coil domain. Homotrimer when
CC       interacts with icosehadral capsid. Interacts with capsid protein, and
CC       with Movement protein (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Host cell junction, host
CC       plasmodesma.
CC   -!- SIMILARITY: Belongs to the caulimovirus ORF III family. {ECO:0000305}.
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DR   EMBL; V00140; CAA23454.1; -; Genomic_DNA.
DR   SMR; P03552; -.
DR   Proteomes; UP000008438; Genome.
DR   GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   InterPro; IPR004986; Caulimo_virion-assoc.
DR   Pfam; PF03310; Cauli_DNA-bind; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Disulfide bond; Host cell junction; Reference proteome;
KW   Virion.
FT   CHAIN           1..129
FT                   /note="Virion-associated protein"
FT                   /id="PRO_0000222076"
FT   REGION          122..129
FT                   /note="Capsid binding"
FT                   /evidence="ECO:0000250"
FT   COILED          1..31
FT                   /evidence="ECO:0000250"
FT   COILED          38..59
FT                   /evidence="ECO:0000250"
FT   DISULFID        60
FT                   /note="Interchain (with C-62 in multimeric partner 1)"
FT                   /evidence="ECO:0000250"
FT   DISULFID        62
FT                   /note="Interchain (with C-60 in multimeric partner 2)"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   129 AA;  14154 MW;  DDCFD31791DD1717 CRC64;
     MANLNQIQKE VSEILSDQKS MKSDIKAILE LLGSQNPTKE SLEAVAAKIV NDLTKLINDC
     PCNKEILEAL GNQPKEQLIE QPKEKGKGLN LGKYTYPNYG VGNEELGSSG NPKALTWPFK
     APAGWPNQF