ID   VAP_CAMVD               Reviewed;         129 AA.
AC   P03553;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Virion-associated protein;
DE            Short=Vap;
DE   AltName: Full=Protein 3;
DE            Short=P3;
GN   ORFNames=ORF III;
OS   Cauliflower mosaic virus (strain D/H) (CaMV).
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Caulimoviridae; Caulimovirus.
OX   NCBI_TaxID=10645;
OH   NCBI_TaxID=3702; Arabidopsis thaliana (Mouse-ear cress).
OH   NCBI_TaxID=3705; Brassica.
OH   NCBI_TaxID=3725; Raphanus.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7152260; DOI=10.1016/0378-1119(82)90013-0;
RA   Balazs E., Guilley H., Jonard G., Richards K.;
RT   "Nucleotide sequence of DNA from an altered-virulence isolate D/H of the
RT   cauliflower mosaic virus.";
RL   Gene 19:239-249(1982).
CC   -!- FUNCTION: Plays a role in virus cell-to-cell and plant-to-plant
CC       transmission. Interacts with virion icosahedral capsid and movement
CC       protein, thereby facilitating virion cell-to-cell transmission through
CC       plasmodesmata opened by viral movement protein. Also interacts with
CC       aphid transmission factor, attaching the virion to aphid stylet when
CC       the animal feeds on an virus infected plant. Aphid saliva may later
CC       detach the virion, inducing release of infectious particles when the
CC       animal feeds on a new plant (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homotetramer, through coiled-coil domain. Homotrimer when
CC       interacts with icosehadral capsid. Interacts with capsid protein, and
CC       with Movement protein (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Host cell junction, host
CC       plasmodesma.
CC   -!- SIMILARITY: Belongs to the caulimovirus ORF III family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M10376; AAA46347.1; -; Genomic_DNA.
DR   SMR; P03553; -.
DR   Proteomes; UP000008439; Genome.
DR   GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   InterPro; IPR004986; Caulimo_virion-assoc.
DR   Pfam; PF03310; Cauli_DNA-bind; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Disulfide bond; Host cell junction; Virion.
FT   CHAIN           1..129
FT                   /note="Virion-associated protein"
FT                   /id="PRO_0000222077"
FT   REGION          122..129
FT                   /note="Capsid binding"
FT                   /evidence="ECO:0000250"
FT   COILED          1..31
FT                   /evidence="ECO:0000250"
FT   COILED          38..59
FT                   /evidence="ECO:0000250"
FT   DISULFID        60
FT                   /note="Interchain (with C-62 in multimeric partner 1)"
FT                   /evidence="ECO:0000250"
FT   DISULFID        62
FT                   /note="Interchain (with C-60 in multimeric partner 2)"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   129 AA;  14110 MW;  D1184908AC9C0706 CRC64;
     MANLNQIQKE VSEILSDQKS MKADIKAILE LLGSQNPIKE SLETVAAKIV NDLTKLINDC
     PCNKEILEAL GNQPKEQLIG QPKEKGKGLN LGKYSYPNYG VGNEELGSSG NPKALTWPFK
     APAGWPNQY