ID   VAP_FMVD                Reviewed;         115 AA.
AC   P09522;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   29-SEP-2021, entry version 57.
DE   RecName: Full=Virion-associated protein;
DE            Short=Vap;
DE   AltName: Full=Protein 3;
DE            Short=P3;
GN   ORFNames=ORF III;
OS   Figwort mosaic virus (strain DxS) (FMV).
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Caulimoviridae; Caulimovirus.
OX   NCBI_TaxID=10650;
OH   NCBI_TaxID=46031; Scrophularia californica (California bee plant).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3671088; DOI=10.1093/nar/15.20.8451;
RA   Richins R.D., Scholthof H.B., Shepherd R.J.;
RT   "Sequence of figwort mosaic virus DNA (caulimovirus group).";
RL   Nucleic Acids Res. 15:8451-8466(1987).
CC   -!- FUNCTION: Plays a role in virus cell-to-cell and plant-to-plant
CC       transmission. Interacts with virion icosahedral capsid and movement
CC       protein, thereby facilitating virion cell-to-cell transmission through
CC       plasmodesmata opened by viral movement protein. Also interacts with
CC       aphid transmission factor, attaching the virion to aphid stylet when
CC       the animal feeds on an virus infected plant. Aphid saliva may later
CC       detach the virion, inducing release of infectious particles when the
CC       animal feeds on a new plant (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homotetramer, through coiled-coil domain. Homotrimer when
CC       interacts with icosehadral capsid. Interacts with capsid protein, and
CC       with Movement protein (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Host cell junction, host
CC       plasmodesma.
CC   -!- SIMILARITY: Belongs to the caulimovirus ORF III family. {ECO:0000305}.
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DR   EMBL; X06166; CAA29525.1; -; Genomic_DNA.
DR   PIR; S01281; S01281.
DR   RefSeq; NP_619546.1; NC_003554.1.
DR   SMR; P09522; -.
DR   GeneID; 940159; -.
DR   KEGG; vg:940159; -.
DR   Proteomes; UP000008622; Genome.
DR   GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   InterPro; IPR004986; Caulimo_virion-assoc.
DR   Pfam; PF03310; Cauli_DNA-bind; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Disulfide bond; Host cell junction; Reference proteome;
KW   Virion.
FT   CHAIN           1..115
FT                   /note="Virion-associated protein"
FT                   /id="PRO_0000222082"
FT   REGION          96..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1..28
FT                   /evidence="ECO:0000255"
FT   COILED          33..54
FT                   /evidence="ECO:0000250"
FT   DISULFID        55
FT                   /note="Interchain (with C-57 in multimeric partner 1)"
FT                   /evidence="ECO:0000250"
FT   DISULFID        57
FT                   /note="Interchain (with C-55 in multimeric partner 2)"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   115 AA;  12675 MW;  ECCCB98646FDE396 CRC64;
     MAATLSEIRE LIQSLTKTAN EIKAMLERNS AGKPTGIEEA AAKIIKDIGD KIDQCECTKK
     IEEMLDQKQN ADTQIVPTKQ ESSGLVKYSY PNWNVGNEEL GSSGNPNAVK WPPRK