ID   VATB2_GOSHI             Reviewed;         386 AA.
AC   Q43433;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=V-type proton ATPase subunit B 2;
DE            Short=V-ATPase subunit B 2;
DE   AltName: Full=Vacuolar proton pump subunit B 2;
DE   Flags: Fragment;
OS   Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX   NCBI_TaxID=3635;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Acala SJ2; TISSUE=Ovule;
RX   PubMed=7972522; DOI=10.1104/pp.106.1.393;
RA   Wan C.Y., Wilkins T.A.;
RT   "Isolation of multiple cDNAs encoding the vacuolar H(+)-ATPase subunit B
RT   from developing cotton (Gossypium hirsutum L.) ovules.";
RL   Plant Physiol. 106:393-394(1994).
CC   -!- FUNCTION: Non-catalytic subunit of the peripheral V1 complex of
CC       vacuolar ATPase. V-ATPase is responsible for acidifying a variety of
CC       intracellular compartments in eukaryotic cells.
CC   -!- SUBUNIT: V-ATPase is a heteromultimeric enzyme composed of a peripheral
CC       catalytic V1 complex (main components: subunits A, B, C, D, E, and F)
CC       attached to an integral membrane V0 proton pore complex (main
CC       component: the proteolipid protein).
CC   -!- SIMILARITY: Belongs to the ATPase alpha/beta chains family.
CC       {ECO:0000305}.
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DR   EMBL; U07053; AAA57550.1; -; mRNA.
DR   AlphaFoldDB; Q43433; -.
DR   SMR; Q43433; -.
DR   PRIDE; Q43433; -.
DR   Proteomes; UP000189702; Genome assembly.
DR   GO; GO:0000221; C:vacuolar proton-transporting V-type ATPase, V1 domain; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IBA:GO_Central.
DR   GO; GO:0007035; P:vacuolar acidification; IBA:GO_Central.
DR   InterPro; IPR020003; ATPase_a/bsu_AS.
DR   InterPro; IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
DR   InterPro; IPR005723; ATPase_V1-cplx_bsu.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR022879; V-ATPase_su_B/beta.
DR   PANTHER; PTHR43389; PTHR43389; 1.
DR   Pfam; PF00006; ATP-synt_ab; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01040; V-ATPase_V1_B; 1.
DR   PROSITE; PS00152; ATPASE_ALPHA_BETA; 1.
PE   2: Evidence at transcript level;
KW   Hydrogen ion transport; Ion transport; Reference proteome; Transport.
FT   CHAIN           <1..386
FT                   /note="V-type proton ATPase subunit B 2"
FT                   /id="PRO_0000144642"
FT   NON_TER         1
SQ   SEQUENCE   386 AA;  43243 MW;  31706640529A62C3 CRC64;
     GRIFNGSGKP IDNGPPILPE AYLDISGSSI NPSERTYPEE MIQTGISTID VMNSIARGQK
     IPFFSAAGLP HNEIAAQICR QAGLVKRLEK AGDLLEDGEE DNFAIVFAAM GVNMETAQFF
     KRDFEENGSM ERVTLFLNLA NDPTIERIIT PRIALTTAEY LAYECGKHVL VILTDMSSYA
     DALREVSAAR EEVPGRRGYP GYMYTDLATI YERAGRIEGR KGSITQIPIL TMPNDDITHP
     TPDLTGYITE GQIYIDRQLH NRQIYPPINV LPSLSRLMKS AIGEGMTRRD HADVSNQLYA
     NYAIGKDVQA MKAVVGEEAL SSEDLLYLEF LDKFERKFVT QGAYDTRNIF QSLDLAWTLL
     RIFPRELLHR IPAKTLDQYY SRDAAN