VATB_THET8
ID VATB_THET8 Reviewed; 478 AA.
AC Q56404; Q5SIU2;
DT 24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT 20-JUN-2003, sequence version 2.
DT 03-AUG-2022, entry version 148.
DE RecName: Full=V-type ATP synthase beta chain;
DE AltName: Full=V-ATPase subunit B;
GN Name=atpB; OrderedLocusNames=TTHA1272;
OS Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8).
OC Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=300852;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1836357; DOI=10.1016/0005-2728(91)90003-7;
RA Tsutsumi S., Denda K., Yokoyama K., Oshima T., Date T., Yoshida M.;
RT "Molecular cloning of genes encoding major two subunits of a eubacterial V-
RT type ATPase from Thermus thermophilus.";
RL Biochim. Biophys. Acta 1098:13-20(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10788522; DOI=10.1074/jbc.275.18.13955;
RA Yokoyama K., Ohkuma S., Taguchi H., Yasunaga T., Wakabayashi T.,
RA Yoshida M.;
RT "V-type H+-ATPase/synthase from a thermophilic eubacterium, Thermus
RT thermophilus. Subunit structure and operon.";
RL J. Biol. Chem. 275:13955-13961(2000).
RN [3]
RP SEQUENCE REVISION TO 75.
RA Yokoyama K., Ohkuma S., Taguchi H., Yasunaga T., Wakabayashi T.,
RA Yoshida M.;
RL Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27634 / DSM 579 / HB8;
RA Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T.,
RA Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.;
RT "Complete genome sequence of Thermus thermophilus HB8.";
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Produces ATP from ADP in the presence of a proton gradient
CC across the membrane. The V-type beta chain is a regulatory subunit.
CC -!- INTERACTION:
CC Q56404; Q56403: atpA; NbExp=2; IntAct=EBI-7260036, EBI-7260009;
CC -!- SIMILARITY: Belongs to the ATPase alpha/beta chains family.
CC {ECO:0000305}.
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DR EMBL; X63855; CAA45341.1; -; Genomic_DNA.
DR EMBL; D63799; BAA09874.2; -; Genomic_DNA.
DR EMBL; AP008226; BAD71095.1; -; Genomic_DNA.
DR PIR; B56812; B56812.
DR RefSeq; WP_011173333.1; NC_006461.1.
DR RefSeq; YP_144538.1; NC_006461.1.
DR PDB; 3A5C; X-ray; 4.51 A; D/E/F/L/M/N=1-478.
DR PDB; 3A5D; X-ray; 4.80 A; D/E/F/L/M/N=1-478.
DR PDB; 3GQB; X-ray; 2.80 A; B/D=1-464.
DR PDB; 3J0J; EM; 9.70 A; D/E/F=1-478.
DR PDB; 3W3A; X-ray; 3.90 A; D/E/F/L/M/N=7-463.
DR PDB; 5GAR; EM; 6.40 A; D/E/F=7-463.
DR PDB; 5GAS; EM; 9.50 A; D/E/F=7-463.
DR PDB; 5TSJ; EM; 8.70 A; D/E/F=7-463.
DR PDB; 5Y5X; EM; 5.00 A; D/E/F=1-478.
DR PDB; 5Y5Y; EM; 4.70 A; D/E/F=1-478.
DR PDB; 5Y5Z; EM; 6.70 A; D/E/F=1-478.
DR PDB; 5Y60; EM; 7.50 A; D/E/F=1-478.
DR PDB; 6LY8; EM; 3.50 A; D/E/F=1-478.
DR PDB; 6QUM; EM; 3.25 A; D/E/F=1-478.
DR PDB; 6R0W; EM; 3.60 A; D/E/F=1-478.
DR PDB; 6R0Y; EM; 3.90 A; D/E/F=1-478.
DR PDB; 6R0Z; EM; 3.80 A; D/E/F=1-478.
DR PDB; 6R10; EM; 4.30 A; D/E/F=1-478.
DR PDBsum; 3A5C; -.
DR PDBsum; 3A5D; -.
DR PDBsum; 3GQB; -.
DR PDBsum; 3J0J; -.
DR PDBsum; 3W3A; -.
DR PDBsum; 5GAR; -.
DR PDBsum; 5GAS; -.
DR PDBsum; 5TSJ; -.
DR PDBsum; 5Y5X; -.
DR PDBsum; 5Y5Y; -.
DR PDBsum; 5Y5Z; -.
DR PDBsum; 5Y60; -.
DR PDBsum; 6LY8; -.
DR PDBsum; 6QUM; -.
DR PDBsum; 6R0W; -.
DR PDBsum; 6R0Y; -.
DR PDBsum; 6R0Z; -.
DR PDBsum; 6R10; -.
DR AlphaFoldDB; Q56404; -.
DR SMR; Q56404; -.
DR IntAct; Q56404; 2.
DR MINT; Q56404; -.
DR STRING; 300852.55772654; -.
DR TCDB; 3.A.2.2.1; the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.
DR EnsemblBacteria; BAD71095; BAD71095; BAD71095.
DR GeneID; 3169042; -.
DR KEGG; ttj:TTHA1272; -.
DR PATRIC; fig|300852.9.peg.1251; -.
DR eggNOG; COG1156; Bacteria.
DR HOGENOM; CLU_022916_0_0_0; -.
DR OMA; ICELRTP; -.
DR PhylomeDB; Q56404; -.
DR EvolutionaryTrace; Q56404; -.
DR Proteomes; UP000000532; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:UniProtKB-UniRule.
DR GO; GO:0042777; P:proton motive force-driven plasma membrane ATP synthesis; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00310; ATP_synth_B_arch; 1.
DR InterPro; IPR020003; ATPase_a/bsu_AS.
DR InterPro; IPR004100; ATPase_F1/V1/A1_a/bsu_N.
DR InterPro; IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR022879; V-ATPase_su_B/beta.
DR PANTHER; PTHR43389; PTHR43389; 1.
DR Pfam; PF00006; ATP-synt_ab; 1.
DR Pfam; PF02874; ATP-synt_ab_N; 1.
DR PIRSF; PIRSF039114; V-ATPsynth_beta/V-ATPase_B; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00152; ATPASE_ALPHA_BETA; 1.
PE 1: Evidence at protein level;
KW 3D-structure; ATP synthesis; Hydrogen ion transport; Ion transport;
KW Reference proteome; Transport.
FT CHAIN 1..478
FT /note="V-type ATP synthase beta chain"
FT /id="PRO_0000144682"
FT CONFLICT 75
FT /note="L -> W (in Ref. 1; CAA45341)"
FT /evidence="ECO:0000305"
FT STRAND 11..15
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 18..23
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 32..36
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 38..40
FT /evidence="ECO:0007829|PDB:6LY8"
FT STRAND 42..61
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 68..70
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 72..79
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 81..84
FT /evidence="ECO:0007829|PDB:3GQB"
FT TURN 87..90
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 91..94
FT /evidence="ECO:0007829|PDB:3GQB"
FT TURN 95..97
FT /evidence="ECO:0007829|PDB:6LY8"
FT STRAND 101..103
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 109..113
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 121..123
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 130..132
FT /evidence="ECO:0007829|PDB:6LY8"
FT HELIX 136..139
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 152..155
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 156..158
FT /evidence="ECO:0007829|PDB:6QUM"
FT HELIX 160..170
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 175..178
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 182..184
FT /evidence="ECO:0007829|PDB:6LY8"
FT STRAND 187..196
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 198..210
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 213..216
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 217..223
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 224..226
FT /evidence="ECO:0007829|PDB:6QUM"
FT HELIX 229..247
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 252..258
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 260..272
FT /evidence="ECO:0007829|PDB:3GQB"
FT TURN 273..275
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 280..282
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 287..295
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 301..303
FT /evidence="ECO:0007829|PDB:6LY8"
FT STRAND 307..316
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 321..323
FT /evidence="ECO:0007829|PDB:6LY8"
FT HELIX 324..332
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 333..339
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 341..345
FT /evidence="ECO:0007829|PDB:3GQB"
FT TURN 354..356
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 362..364
FT /evidence="ECO:0007829|PDB:3GQB"
FT TURN 368..370
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 375..395
FT /evidence="ECO:0007829|PDB:3GQB"
FT STRAND 397..399
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 407..410
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 413..420
FT /evidence="ECO:0007829|PDB:3GQB"
FT TURN 421..423
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 432..443
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 448..450
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 456..462
FT /evidence="ECO:0007829|PDB:3GQB"
FT HELIX 467..470
FT /evidence="ECO:0007829|PDB:6QUM"
SQ SEQUENCE 478 AA; 53160 MW; 43ABBFA6931AAFF3 CRC64;
MDLLKKEYTG ITYISGPLLF VENAKDLAYG AIVDIKDGTG RVRGGQVIEV SEEYAVIQVF
EETTGLDLAT TSVSLVEDVA RLGVSKEMLG RRFNGIGKPI DGLPPITPEK RLPITGLPLN
PVARRKPEQF IQTGISTIDV MNTLVRGQKL PIFSGSGLPA NEIAAQIARQ ATVRPDLSGE
GEKEEPFAVV FAAMGITQRE LSYFIQEFER TGALSRSVLF LNKADDPTIE RILTPRMALT
VAEYLAFEHD YHVLVILTDM TNYCEALREI GAAREEIPGR RGYPGYMYTD LATIYERAGV
VEGKKGSVTQ IPILSMPDDD RTHPIPDLTG YITEGQIQLS RELHRKGIYP PIDPLPSLSR
LMNNGVGKGK TREDHKQVSD QLYSAYANGV DIRKLVAIIG EDALTENDRR YLQFADAFER
FFINQGQQNR SIEESLQIAW ALLSMLPQGE LKRISKDHIG KYYGQKLEEI WGAPQALD
