VATC_THET8
ID VATC_THET8 Reviewed; 323 AA.
AC P74902; Q5SIT9;
DT 24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=V-type ATP synthase subunit C;
DE AltName: Full=V-ATPase subunit C;
GN Name=atpC; OrderedLocusNames=TTHA1275;
OS Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8).
OC Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=300852;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10788522; DOI=10.1074/jbc.275.18.13955;
RA Yokoyama K., Ohkuma S., Taguchi H., Yasunaga T., Wakabayashi T.,
RA Yoshida M.;
RT "V-type H+-ATPase/synthase from a thermophilic eubacterium, Thermus
RT thermophilus. Subunit structure and operon.";
RL J. Biol. Chem. 275:13955-13961(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27634 / DSM 579 / HB8;
RA Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T.,
RA Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.;
RT "Complete genome sequence of Thermus thermophilus HB8.";
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Produces ATP from ADP in the presence of a proton gradient
CC across the membrane.
CC -!- SIMILARITY: Belongs to the V-ATPase V0D/AC39 subunit family.
CC {ECO:0000305}.
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DR EMBL; D63799; BAA09871.1; -; Genomic_DNA.
DR EMBL; AP008226; BAD71098.1; -; Genomic_DNA.
DR RefSeq; WP_011228562.1; NC_006461.1.
DR RefSeq; YP_144541.1; NC_006461.1.
DR PDB; 1R5Z; X-ray; 1.95 A; A/B/C=1-323.
DR PDB; 1V9M; X-ray; 1.85 A; A=1-323.
DR PDB; 3J0J; EM; 9.70 A; M=1-323.
DR PDB; 5GAR; EM; 6.40 A; M=1-323.
DR PDB; 5GAS; EM; 9.50 A; M=1-323.
DR PDB; 5TSJ; EM; 8.70 A; M=1-323.
DR PDB; 5Y5X; EM; 5.00 A; M=1-323.
DR PDB; 5Y5Y; EM; 4.70 A; M=1-323.
DR PDB; 5Y5Z; EM; 6.70 A; M=1-323.
DR PDB; 5Y60; EM; 7.50 A; M=1-323.
DR PDB; 6LY9; EM; 3.93 A; M=1-323.
DR PDB; 6QUM; EM; 3.25 A; M=1-323.
DR PDB; 6R0W; EM; 3.60 A; M=1-323.
DR PDB; 6R0Y; EM; 3.90 A; M=1-323.
DR PDB; 6R0Z; EM; 3.80 A; M=1-323.
DR PDB; 6R10; EM; 4.30 A; M=1-323.
DR PDBsum; 1R5Z; -.
DR PDBsum; 1V9M; -.
DR PDBsum; 3J0J; -.
DR PDBsum; 5GAR; -.
DR PDBsum; 5GAS; -.
DR PDBsum; 5TSJ; -.
DR PDBsum; 5Y5X; -.
DR PDBsum; 5Y5Y; -.
DR PDBsum; 5Y5Z; -.
DR PDBsum; 5Y60; -.
DR PDBsum; 6LY9; -.
DR PDBsum; 6QUM; -.
DR PDBsum; 6R0W; -.
DR PDBsum; 6R0Y; -.
DR PDBsum; 6R0Z; -.
DR PDBsum; 6R10; -.
DR AlphaFoldDB; P74902; -.
DR SMR; P74902; -.
DR IntAct; P74902; 1.
DR STRING; 300852.55772657; -.
DR TCDB; 3.A.2.2.1; the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.
DR EnsemblBacteria; BAD71098; BAD71098; BAD71098.
DR GeneID; 3168086; -.
DR KEGG; ttj:TTHA1275; -.
DR PATRIC; fig|300852.9.peg.1254; -.
DR eggNOG; COG1527; Bacteria.
DR HOGENOM; CLU_073549_0_0_0; -.
DR OMA; LRKFDVW; -.
DR PhylomeDB; P74902; -.
DR EvolutionaryTrace; P74902; -.
DR Proteomes; UP000000532; Chromosome.
DR GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:UniProtKB-UniRule.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR GO; GO:0042777; P:proton motive force-driven plasma membrane ATP synthesis; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.132.50; -; 1.
DR Gene3D; 1.20.1690.10; -; 2.
DR HAMAP; MF_00314; ATP_synth_C_arch; 1.
DR InterPro; IPR036079; ATPase_su_c/d_sf.
DR InterPro; IPR014272; ATPase_V0-cplx_c_su.
DR InterPro; IPR002843; ATPase_V0-cplx_csu/dsu.
DR InterPro; IPR044911; V-type_ATPase_su_c/d_dom_3.
DR InterPro; IPR035067; V-type_ATPase_suC/d.
DR Pfam; PF01992; vATP-synt_AC39; 1.
DR SUPFAM; SSF103486; SSF103486; 1.
PE 1: Evidence at protein level;
KW 3D-structure; ATP synthesis; Hydrogen ion transport; Ion transport;
KW Reference proteome; Transport.
FT CHAIN 1..323
FT /note="V-type ATP synthase subunit C"
FT /id="PRO_0000119376"
FT HELIX 6..16
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 22..28
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 33..41
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 44..48
FT /evidence="ECO:0007829|PDB:1V9M"
FT STRAND 51..53
FT /evidence="ECO:0007829|PDB:1R5Z"
FT HELIX 54..68
FT /evidence="ECO:0007829|PDB:1V9M"
FT TURN 69..71
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 72..75
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 78..104
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 109..111
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 121..129
FT /evidence="ECO:0007829|PDB:1V9M"
FT STRAND 130..132
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 133..141
FT /evidence="ECO:0007829|PDB:1V9M"
FT TURN 142..144
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 146..155
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 161..177
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 187..206
FT /evidence="ECO:0007829|PDB:1V9M"
FT TURN 207..209
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 214..216
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 227..234
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 238..242
FT /evidence="ECO:0007829|PDB:1V9M"
FT STRAND 246..248
FT /evidence="ECO:0007829|PDB:6QUM"
FT HELIX 250..252
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 258..273
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 274..278
FT /evidence="ECO:0007829|PDB:1V9M"
FT STRAND 280..282
FT /evidence="ECO:0007829|PDB:1R5Z"
FT HELIX 284..309
FT /evidence="ECO:0007829|PDB:1V9M"
FT HELIX 313..319
FT /evidence="ECO:0007829|PDB:1V9M"
SQ SEQUENCE 323 AA; 35919 MW; 30C7E41C8490CD57 CRC64;
MADDFAYLNA RVRVRRGTLL KESFFQEALD LSFADFLRLL SETVYGGELA GQGLPDVDRA
VLRTQAKLVG DLPRLVTGEA REAVRLLLLR NDLHNLQALL RAKATGRPFE EVLLLPGTLR
EEVWRQAYEA QDPAGMAQVL AVPGHPLARA LRAVLRETQD LARVEALLAK RFFEDVAKAA
KGLDQPALRD YLALEVDAEN LRTAFKLQGS GLAPDAFFLK GGRFVDRVRF ARLMEGDYAV
LDELSGTPFS GLSGVRDLKA LERGLRCVLL KEAKKGVQDP LGVGLVLAYV KEREWEAVRL
RLLARRAYFG LPRAQVEEEV VCP
