ID   VATD2_TREPA             Reviewed;         209 AA.
AC   O83539;
DT   24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=V-type ATP synthase subunit D 2;
DE   AltName: Full=V-ATPase subunit D 2;
GN   Name=atpD2; OrderedLocusNames=TP_0527;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- FUNCTION: Produces ATP from ADP in the presence of a proton gradient
CC       across the membrane. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the V-ATPase D subunit family. {ECO:0000305}.
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DR   EMBL; AE000520; AAC65514.1; -; Genomic_DNA.
DR   PIR; A71313; A71313.
DR   RefSeq; WP_010881975.1; NC_021490.2.
DR   AlphaFoldDB; O83539; -.
DR   SMR; O83539; -.
DR   IntAct; O83539; 18.
DR   STRING; 243276.TPANIC_0527; -.
DR   TCDB; 3.A.2.3.3; the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.
DR   EnsemblBacteria; AAC65514; AAC65514; TP_0527.
DR   GeneID; 57879051; -.
DR   KEGG; tpa:TP_0527; -.
DR   eggNOG; COG1394; Bacteria.
DR   HOGENOM; CLU_069688_2_0_12; -.
DR   OMA; SKNIMGV; -.
DR   OrthoDB; 1334900at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:UniProtKB-UniRule.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0042777; P:proton motive force-driven plasma membrane ATP synthesis; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00271; ATP_synth_D_arch; 1.
DR   InterPro; IPR002699; V_ATPase_D.
DR   PANTHER; PTHR11671; PTHR11671; 1.
DR   Pfam; PF01813; ATP-synt_D; 1.
DR   TIGRFAMs; TIGR00309; V_ATPase_subD; 1.
PE   3: Inferred from homology;
KW   ATP synthesis; Hydrogen ion transport; Ion transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..209
FT                   /note="V-type ATP synthase subunit D 2"
FT                   /id="PRO_0000144274"
SQ   SEQUENCE   209 AA;  23926 MW;  0647A0E11B7DE62B CRC64;
     MKTPLAPTKS NLAYVRDQLG LARDGYRLLE QKREILFMEL TSLLEEVHLL ETELDKRRKQ
     AYASLWQLLL AQGRDDIAAC ALVTPVPCRV QQEVLLIAGL RFLRLDAVMQ PPKLQYAALG
     SSACMDRARE DFGLLLQTLT RMASVQTIVW RLASEMRKTQ RRVNALSKQI IPQMCETCMY
     IESVLEERDR ESTFVLKSLK ARKDPTTTL