VATD_THET8
ID VATD_THET8 Reviewed; 223 AA.
AC O87880; Q5SIU3;
DT 24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2001, sequence version 2.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=V-type ATP synthase subunit D;
DE AltName: Full=V-ATPase subunit D;
GN Name=atpD; Synonyms=vatD; OrderedLocusNames=TTHA1271;
OS Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8).
OC Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=300852;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10788522; DOI=10.1074/jbc.275.18.13955;
RA Yokoyama K., Ohkuma S., Taguchi H., Yasunaga T., Wakabayashi T.,
RA Yoshida M.;
RT "V-type H+-ATPase/synthase from a thermophilic eubacterium, Thermus
RT thermophilus. Subunit structure and operon.";
RL J. Biol. Chem. 275:13955-13961(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27634 / DSM 579 / HB8;
RA Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T.,
RA Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.;
RT "Complete genome sequence of Thermus thermophilus HB8.";
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Produces ATP from ADP in the presence of a proton gradient
CC across the membrane.
CC -!- SIMILARITY: Belongs to the V-ATPase D subunit family. {ECO:0000305}.
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DR EMBL; D63799; BAA33198.2; -; Genomic_DNA.
DR EMBL; AP008226; BAD71094.1; -; Genomic_DNA.
DR RefSeq; WP_011173332.1; NC_006461.1.
DR RefSeq; YP_144537.1; NC_006461.1.
DR PDB; 3A5C; X-ray; 4.51 A; G/O=1-223.
DR PDB; 3A5D; X-ray; 4.80 A; G/O=1-223.
DR PDB; 3J0J; EM; 9.70 A; G=1-223.
DR PDB; 3W3A; X-ray; 3.90 A; G/O=2-211.
DR PDB; 5GAR; EM; 6.40 A; K=2-211.
DR PDB; 5GAS; EM; 9.50 A; K=2-211.
DR PDB; 5TSJ; EM; 8.70 A; K=2-211.
DR PDB; 5Y5X; EM; 5.00 A; G=1-223.
DR PDB; 5Y5Y; EM; 4.70 A; G=1-223.
DR PDB; 5Y5Z; EM; 6.70 A; G=1-223.
DR PDB; 5Y60; EM; 7.50 A; G=1-223.
DR PDB; 6LY8; EM; 3.50 A; G=1-223.
DR PDB; 6QUM; EM; 3.25 A; G=1-223.
DR PDB; 6R0W; EM; 3.60 A; G=1-223.
DR PDB; 6R0Y; EM; 3.90 A; G=1-223.
DR PDB; 6R0Z; EM; 3.80 A; G=1-223.
DR PDB; 6R10; EM; 4.30 A; G=1-223.
DR PDBsum; 3A5C; -.
DR PDBsum; 3A5D; -.
DR PDBsum; 3J0J; -.
DR PDBsum; 3W3A; -.
DR PDBsum; 5GAR; -.
DR PDBsum; 5GAS; -.
DR PDBsum; 5TSJ; -.
DR PDBsum; 5Y5X; -.
DR PDBsum; 5Y5Y; -.
DR PDBsum; 5Y5Z; -.
DR PDBsum; 5Y60; -.
DR PDBsum; 6LY8; -.
DR PDBsum; 6QUM; -.
DR PDBsum; 6R0W; -.
DR PDBsum; 6R0Y; -.
DR PDBsum; 6R0Z; -.
DR PDBsum; 6R10; -.
DR AlphaFoldDB; O87880; -.
DR SMR; O87880; -.
DR IntAct; O87880; 2.
DR MINT; O87880; -.
DR STRING; 300852.55772653; -.
DR TCDB; 3.A.2.2.1; the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.
DR EnsemblBacteria; BAD71094; BAD71094; BAD71094.
DR GeneID; 3168073; -.
DR KEGG; ttj:TTHA1271; -.
DR PATRIC; fig|300852.9.peg.1250; -.
DR eggNOG; COG1394; Bacteria.
DR HOGENOM; CLU_069688_2_1_0; -.
DR OMA; SKNIMGV; -.
DR PhylomeDB; O87880; -.
DR EvolutionaryTrace; O87880; -.
DR Proteomes; UP000000532; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:UniProtKB-UniRule.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR GO; GO:0042777; P:proton motive force-driven plasma membrane ATP synthesis; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00271; ATP_synth_D_arch; 1.
DR InterPro; IPR002699; V_ATPase_D.
DR PANTHER; PTHR11671; PTHR11671; 1.
DR Pfam; PF01813; ATP-synt_D; 1.
DR TIGRFAMs; TIGR00309; V_ATPase_subD; 1.
PE 1: Evidence at protein level;
KW 3D-structure; ATP synthesis; Hydrogen ion transport; Ion transport;
KW Reference proteome; Transport.
FT CHAIN 1..223
FT /note="V-type ATP synthase subunit D"
FT /id="PRO_0000144272"
FT REGION 203..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT HELIX 8..70
FT /evidence="ECO:0007829|PDB:6QUM"
FT HELIX 73..82
FT /evidence="ECO:0007829|PDB:6QUM"
FT STRAND 90..96
FT /evidence="ECO:0007829|PDB:6QUM"
FT STRAND 99..105
FT /evidence="ECO:0007829|PDB:6QUM"
FT STRAND 119..122
FT /evidence="ECO:0007829|PDB:6QUM"
FT HELIX 123..168
FT /evidence="ECO:0007829|PDB:6QUM"
FT HELIX 170..208
FT /evidence="ECO:0007829|PDB:6QUM"
SQ SEQUENCE 223 AA; 24678 MW; B666AE00DFE0B08B CRC64;
MSQVSPTRMN LLQRRGQLRL AQKGVDLLKK KRDALVAEFF GLVREAMEAR KALDQAAKEA
YAALLLAQAF DGPEVVAGAA LGVPPLEGVE AEVENVWGSK VPRLKATFPD GALLSPVGTP
AYTLEASRAF RRYAEALIRV ANTETRLKKI GEEIKKTTRR VNALEQVVIP GIRAQIRFIQ
QVLEQRERED TFRLKRIKGK IEAREAEEEG GRPNPQVEIG AGL
