ID   VATE_PYRHO              Reviewed;         198 AA.
AC   O57724;
DT   24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=V-type ATP synthase subunit E;
DE   AltName: Full=V-ATPase subunit E;
GN   Name=atpE; OrderedLocusNames=PH1978;
OS   Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS   100139 / OT-3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=70601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX   PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA   Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA   Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA   Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA   Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
CC   -!- FUNCTION: Produces ATP from ADP in the presence of a proton gradient
CC       across the membrane. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the V-ATPase E subunit family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000001; BAA31105.1; -; Genomic_DNA.
DR   PIR; B71214; B71214.
DR   RefSeq; WP_010886042.1; NC_000961.1.
DR   PDB; 2DM9; X-ray; 1.85 A; A/B=1-198.
DR   PDB; 2DMA; X-ray; 2.05 A; A=1-198.
DR   PDB; 4DT0; X-ray; 3.65 A; A=2-198.
DR   PDBsum; 2DM9; -.
DR   PDBsum; 2DMA; -.
DR   PDBsum; 4DT0; -.
DR   AlphaFoldDB; O57724; -.
DR   SMR; O57724; -.
DR   STRING; 70601.3258422; -.
DR   EnsemblBacteria; BAA31105; BAA31105; BAA31105.
DR   GeneID; 1442824; -.
DR   KEGG; pho:PH1978; -.
DR   eggNOG; arCOG00869; Archaea.
DR   OMA; YAGNIDC; -.
DR   OrthoDB; 93762at2157; -.
DR   BRENDA; 7.1.2.2; 5244.
DR   EvolutionaryTrace; O57724; -.
DR   Proteomes; UP000000752; Chromosome.
DR   GO; GO:0033178; C:proton-transporting two-sector ATPase complex, catalytic domain; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:UniProtKB-UniRule.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0042777; P:proton motive force-driven plasma membrane ATP synthesis; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.2320.30; -; 1.
DR   HAMAP; MF_00311; ATP_synth_E_arch; 1.
DR   InterPro; IPR028987; ATP_synth_B-like_membr_sf.
DR   InterPro; IPR038495; ATPase_E_C.
DR   InterPro; IPR002842; ATPase_V1_Esu.
DR   PANTHER; PTHR45715; PTHR45715; 1.
DR   Pfam; PF01991; vATP-synt_E; 1.
DR   SUPFAM; SSF81573; SSF81573; 1.
PE   1: Evidence at protein level;
KW   3D-structure; ATP synthesis; Hydrogen ion transport; Ion transport;
KW   Transport.
FT   CHAIN           1..198
FT                   /note="V-type ATP synthase subunit E"
FT                   /id="PRO_0000117322"
FT   HELIX           82..96
FT                   /evidence="ECO:0007829|PDB:2DM9"
FT   HELIX           99..117
FT                   /evidence="ECO:0007829|PDB:2DM9"
FT   STRAND          120..125
FT                   /evidence="ECO:0007829|PDB:2DM9"
FT   HELIX           128..136
FT                   /evidence="ECO:0007829|PDB:2DM9"
FT   HELIX           138..144
FT                   /evidence="ECO:0007829|PDB:2DM9"
FT   STRAND          149..152
FT                   /evidence="ECO:0007829|PDB:2DM9"
FT   STRAND          159..166
FT                   /evidence="ECO:0007829|PDB:2DM9"
FT   STRAND          172..176
FT                   /evidence="ECO:0007829|PDB:2DM9"
FT   HELIX           177..183
FT                   /evidence="ECO:0007829|PDB:2DM9"
FT   HELIX           185..197
FT                   /evidence="ECO:0007829|PDB:2DM9"
SQ   SEQUENCE   198 AA;  22888 MW;  4B12A0485F897CD2 CRC64;
     MNGAELIIQE INKEAERKIE YILNEARQQA EKIKEEARRN AEAKAEWIIR RAKTQAELEK
     QRIIANARLE VRRKRLAIQE EIISSVLEEV KRRLETMSED EYFESVKALL KEAIKELNEK
     KVRVMSNEKT LGLIASRIEE IKSELGDVSI ELGETVDTMG GVIVETEDGR IRIDNTFEAR
     MERFEGEIRS TIAKVLFG