ID   VATG_DICDI              Reviewed;         107 AA.
AC   Q54Z13;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-MAY-2006, sequence version 2.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=V-type proton ATPase subunit G;
DE            Short=V-ATPase subunit G;
DE   AltName: Full=Vacuolar proton pump subunit G;
GN   Name=atp6v1g; Synonyms=vatg; ORFNames=DDB_G0277971;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=AX2;
RX   PubMed=16926386; DOI=10.1074/mcp.m600113-mcp200;
RA   Gotthardt D., Blancheteau V., Bosserhoff A., Ruppert T., Delorenzi M.,
RA   Soldati T.;
RT   "Proteomics fingerprinting of phagosome maturation and evidence for the
RT   role of a Galpha during uptake.";
RL   Mol. Cell. Proteomics 5:2228-2243(2006).
CC   -!- FUNCTION: Catalytic subunit of the peripheral V1 complex of vacuolar
CC       ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of
CC       intracellular compartments in eukaryotic cells.
CC   -!- SUBUNIT: V-ATPase is a heteromultimeric enzyme composed of a peripheral
CC       catalytic V1 complex (components A to H) attached to an integral
CC       membrane V0 proton pore complex (components: a, c, c', c'' and d).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the V-ATPase G subunit family. {ECO:0000305}.
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DR   EMBL; AAFI02000023; EAL68158.2; -; Genomic_DNA.
DR   RefSeq; XP_642039.2; XM_636947.2.
DR   AlphaFoldDB; Q54Z13; -.
DR   SMR; Q54Z13; -.
DR   STRING; 44689.DDB0238144; -.
DR   PaxDb; Q54Z13; -.
DR   EnsemblProtists; EAL68158; EAL68158; DDB_G0277971.
DR   GeneID; 8621251; -.
DR   KEGG; ddi:DDB_G0277971; -.
DR   dictyBase; DDB_G0277971; vatG.
DR   eggNOG; KOG1772; Eukaryota.
DR   HOGENOM; CLU_125101_2_1_1; -.
DR   InParanoid; Q54Z13; -.
DR   OMA; HSKGNEQ; -.
DR   Reactome; R-DDI-1222556; ROS and RNS production in phagocytes.
DR   Reactome; R-DDI-77387; Insulin receptor recycling.
DR   Reactome; R-DDI-917977; Transferrin endocytosis and recycling.
DR   Reactome; R-DDI-9639288; Amino acids regulate mTORC1.
DR   PRO; PR:Q54Z13; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0031164; C:contractile vacuolar membrane; TAS:dictyBase.
DR   GO; GO:0045335; C:phagocytic vesicle; HDA:dictyBase.
DR   GO; GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IBA:GO_Central.
DR   GO; GO:0000221; C:vacuolar proton-transporting V-type ATPase, V1 domain; ISS:dictyBase.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   InterPro; IPR005124; V-ATPase_G.
DR   PANTHER; PTHR12713; PTHR12713; 1.
DR   Pfam; PF03179; V-ATPase_G; 1.
DR   TIGRFAMs; TIGR01147; V_ATP_synt_G; 1.
PE   1: Evidence at protein level;
KW   Hydrogen ion transport; Ion transport; Reference proteome; Transport.
FT   CHAIN           1..107
FT                   /note="V-type proton ATPase subunit G"
FT                   /id="PRO_0000328303"
SQ   SEQUENCE   107 AA;  12199 MW;  67BC44D8A9A11499 CRC64;
     MSSEDGIKKL LDAERTAQKI VADARQDRVQ KLKKAVEEAE KEIKEFREKK DKEYKEYESK
     YLGASSETAS QLATNANKEI DTIRNETAAN KQKVVDLLIK YAITCDN