ID   VATI1_TREPA             Reviewed;         622 AA.
AC   O83444;
DT   24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 127.
DE   RecName: Full=V-type ATP synthase subunit I 1;
DE   AltName: Full=V-ATPase subunit I 1;
GN   Name=atpI1; OrderedLocusNames=TP_0429;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- FUNCTION: Produces ATP from ADP in the presence of a proton gradient
CC       across the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000305}.
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DR   EMBL; AE000520; AAC65415.1; -; Genomic_DNA.
DR   PIR; B71326; B71326.
DR   RefSeq; WP_010881877.1; NC_021490.2.
DR   AlphaFoldDB; O83444; -.
DR   SMR; O83444; -.
DR   STRING; 243276.TPANIC_0429; -.
DR   TCDB; 3.A.2.3.3; the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.
DR   EnsemblBacteria; AAC65415; AAC65415; TP_0429.
DR   KEGG; tpa:TP_0429; -.
DR   eggNOG; COG1269; Bacteria.
DR   HOGENOM; CLU_025558_1_1_12; -.
DR   OMA; INESYAW; -.
DR   OrthoDB; 259071at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Hydrogen ion transport; Ion transport; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..622
FT                   /note="V-type ATP synthase subunit I 1"
FT                   /id="PRO_0000119242"
FT   TRANSMEM        306..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        328..348
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        373..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        428..448
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        459..479
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        485..505
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        532..552
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        562..582
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   622 AA;  69077 MW;  2AECAD4E47821C91 CRC64;
     MIVPMKKVTL LVLGSEQERS LQALRSFGAV HVQLRECASE QLAELHALDA RCVQAIALVT
     DAQTKNVTRG EECRVAGQVV EAAEAVEQIV RTHSDRVELA QRIAQCIAHL ERCEPWGDFD
     PADVRALAQR GIHLIPVELS ERSYRCLPDE LQTLCLARRG GLVRCVLVAD KPGLPPSLPA
     DARALELPDV SPADLFVRLR QLREECATLT QRLLAYSEYQ GAIRALRQKI AADIEFERVH
     LSMVSVDVSQ WRETGETLRI AHVSGYLPVS RVRAFSECAR KEAWAYCCVD PMPEDPVPTQ
     LRNNRWVNLI SPLMNFLGTV PGYWEVDISG FFLLFFGVFF SIIFADAGYG AVLTLVSLGG
     IVLSKRKHAV VSPAWCLGLY LGTLTMVWGA LVCNWFGVPV QYVPASLARI AVWEISGFAD
     AAQRNKNQMH VCFFLGLLHL CLGHLIVVRR TFRSLRVLAE FGSLLMLGGM YVVVLNLIVD
     KERYPLTGMI VGSIIAGFVL NFIFVNYRVS VRQSVADSMK NVINALLGIV NVFADVMSYI
     RLWAVGLAGG AISATVNEMT HPLFANFLAF LGIVLLLFGH GLNYVMSILS VIVHGVRLNT
     LEFSNHVGLM WTGIRYTPFR ER