ID   VATI_AERPE              Reviewed;         685 AA.
AC   Q9YEA0;
DT   24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   26-JUN-2007, sequence version 2.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=V-type ATP synthase subunit I;
DE   AltName: Full=V-ATPase subunit I;
GN   Name=atpI; OrderedLocusNames=APE_0673.1;
OS   Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 /
OS   K1).
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC   Desulfurococcaceae; Aeropyrum.
OX   NCBI_TaxID=272557;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1;
RX   PubMed=10382966; DOI=10.1093/dnares/6.2.83;
RA   Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K.,
RA   Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A.,
RA   Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S.,
RA   Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A.,
RA   Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H.;
RT   "Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon,
RT   Aeropyrum pernix K1.";
RL   DNA Res. 6:83-101(1999).
CC   -!- FUNCTION: Produces ATP from ADP in the presence of a proton gradient
CC       across the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000305}.
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DR   EMBL; BA000002; BAA79646.2; -; Genomic_DNA.
DR   PIR; F72655; F72655.
DR   AlphaFoldDB; Q9YEA0; -.
DR   SMR; Q9YEA0; -.
DR   STRING; 272557.APE_0673.1; -.
DR   PRIDE; Q9YEA0; -.
DR   EnsemblBacteria; BAA79646; BAA79646; APE_0673.1.
DR   KEGG; ape:APE_0673.1; -.
DR   eggNOG; arCOG04138; Archaea.
DR   Proteomes; UP000002518; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Hydrogen ion transport; Ion transport; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..685
FT                   /note="V-type ATP synthase subunit I"
FT                   /id="PRO_0000119226"
FT   TRANSMEM        172..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        348..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        394..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        464..484
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        538..558
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        604..624
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        626..646
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   685 AA;  75021 MW;  871DDDACD43E4C90 CRC64;
     MLLPRMLEEV VLAVPARDYD RVVAGLAVEG IFHVDSPPQG VKGEVDRSYR ALLTQASERS
     SRIRQYFDLA GVEPYRVSGV EIEVGGWGES WKRYLEKYSG VEKFYSGLLE EYSEAEARLK
     ELLDIEARIA PVAHLDVDIA RLYRSGAFDF AVYYGSYSEG LESRVGEIVS RVGGLAAVEA
     SGGSVVVAVA VPKGALSKIS PEILRLNLSI YTPPEGVPGS PREAMEYIRG EKARLGRRLV
     SIQEMASERL GELAEFYTVV TAFENIFKFL VSTLRRGETR IVRGFVDVRD SGRLRSIVDR
     MTRGSYVLLS LGVRRGGEAP IPSKVDLPQF LKPFSRVVEL YGYPEPNEIV PTVFLAITLP
     LTFALMFPDA GQGLLVLLFS LFYLRRVSRD WAYVIAVMGG ASVVSGLLAG EVFGPLVSKM
     LGLPELWYRL GLETPPYAMP TYAIDHGEEE LVPVLVYRAL NVSLFMGAFM LSFGTFLGVV
     NGVIKRDWVG LVESRLPRFL LFASITGPFL VYMDAGEAGS VLRQALLELG GDSIAAKLVL
     AGSVLGLAWM LLAGPIIYML EGHSPLAGLA NSFLEAYESL LMLVGNIPSF LRIMALALAH
     SSLMFVIYYL TVMIMQGGIL ADVVGALLYV GGNLAVAAME GLLAFAHASR LHFYEWFSKF
     YSGTGVPYTP IKVEGVRIKI AGQTF