ID   VATI_CHLTR              Reviewed;         649 AA.
AC   O84307;
DT   24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 117.
DE   RecName: Full=V-type ATP synthase subunit I;
DE   AltName: Full=V-ATPase subunit I;
GN   Name=atpI; OrderedLocusNames=CT_305;
OS   Chlamydia trachomatis (strain D/UW-3/Cx).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=272561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D/UW-3/Cx;
RX   PubMed=9784136; DOI=10.1126/science.282.5389.754;
RA   Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L.,
RA   Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.;
RT   "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia
RT   trachomatis.";
RL   Science 282:754-759(1998).
CC   -!- FUNCTION: Produces ATP from ADP in the presence of a proton gradient
CC       across the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000305}.
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DR   EMBL; AE001273; AAC67898.1; -; Genomic_DNA.
DR   PIR; G71530; G71530.
DR   RefSeq; NP_219810.1; NC_000117.1.
DR   RefSeq; WP_010725153.1; NC_000117.1.
DR   AlphaFoldDB; O84307; -.
DR   STRING; 813.O172_01635; -.
DR   PRIDE; O84307; -.
DR   EnsemblBacteria; AAC67898; AAC67898; CT_305.
DR   GeneID; 884819; -.
DR   KEGG; ctr:CT_305; -.
DR   PATRIC; fig|272561.5.peg.326; -.
DR   HOGENOM; CLU_025558_1_1_0; -.
DR   InParanoid; O84307; -.
DR   OMA; MAVNIMA; -.
DR   Proteomes; UP000000431; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IBA:GO_Central.
DR   GO; GO:0051117; F:ATPase binding; IBA:GO_Central.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0007035; P:vacuolar acidification; IBA:GO_Central.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Hydrogen ion transport; Ion transport; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..649
FT                   /note="V-type ATP synthase subunit I"
FT                   /id="PRO_0000119240"
FT   TRANSMEM        312..332
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        360..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        453..473
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        485..505
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        520..540
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        556..576
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        593..613
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   649 AA;  73214 MW;  1D3FC48CF49850FB CRC64;
     MRVDVDKYLF IGREKSEFFS ACREIGAVEF LSKSKLKDSE KVRKLSEGLK VLNLLTKSCS
     PADLVSTKSG YLVTEQLLQE IFDLNQEITT LTESLKALGK EIVRVKPLGD FSSEEIRELT
     LKTGLAVRFL YKRHIEGAPL EVEEENVFYL ATAYNYDYYA VIGIVSLSKD IFTEIEAPRS
     VNELREEEGH LQALLRKKKA RVCELYAYRE DLLEALCEQC NEQSLQHAEV SAEDLFDDKV
     FSALGWVIVD RLDEVKKLCD SLGIYLERVQ PDPDEVIPTY LENHGLGALG ESLVNIYDTP
     ASTDKDPSLW VFFSFFVFFS MIINDAGYGL VFLATSLFLS FKARKQIKRS IALKRFLQMF
     MILGLGCVCW GGATTSFFGV SVSYTSPFRE YSLTHFLALK KAEYYLKERP KGYKELVHDY
     PILKEKKTPK EFLLAQSTSS GDSVYKAVVY DKFIDNILME IALLVGVVHL SLGMLRYCRQ
     RYSSIGWVIF MCGAYMYLPI YLQAVSLIHY ALHIPYELGG LVGYYVAFIG LGVAILGGVI
     QRGLRGLDEI TAVIQVFSDV LSYLRLYALS LAGAMVGNTV MVMSERFSPA VGILIIIFGH
     TVNIALSIMG GVIHGLRLNF IEWYHYSFDG GGKLLHPLKK VICQKSQNL