ID   VATI_DEIRA              Reviewed;         690 AA.
AC   Q9RWH3;
DT   24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 120.
DE   RecName: Full=V-type ATP synthase subunit I;
DE   AltName: Full=V-ATPase subunit I;
GN   Name=atpI; OrderedLocusNames=DR_0695;
OS   Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG
OS   4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422).
OC   Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae;
OC   Deinococcus.
OX   NCBI_TaxID=243230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB
RC   9279 / R1 / VKM B-1422;
RX   PubMed=10567266; DOI=10.1126/science.286.5444.1571;
RA   White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D.,
RA   Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L.,
RA   Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M.,
RA   Vamathevan J.J., Lam P., McDonald L.A., Utterback T.R., Zalewski C.,
RA   Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D.,
RA   Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C.,
RA   Fraser C.M.;
RT   "Genome sequence of the radioresistant bacterium Deinococcus radiodurans
RT   R1.";
RL   Science 286:1571-1577(1999).
CC   -!- FUNCTION: Produces ATP from ADP in the presence of a proton gradient
CC       across the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000305}.
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DR   EMBL; AE000513; AAF10273.1; -; Genomic_DNA.
DR   PIR; D75487; D75487.
DR   RefSeq; NP_294418.1; NC_001263.1.
DR   RefSeq; WP_010887340.1; NZ_CP015081.1.
DR   AlphaFoldDB; Q9RWH3; -.
DR   SMR; Q9RWH3; -.
DR   STRING; 243230.DR_0695; -.
DR   EnsemblBacteria; AAF10273; AAF10273; DR_0695.
DR   KEGG; dra:DR_0695; -.
DR   PATRIC; fig|243230.17.peg.873; -.
DR   eggNOG; COG1269; Bacteria.
DR   HOGENOM; CLU_025558_2_1_0; -.
DR   InParanoid; Q9RWH3; -.
DR   OMA; MAVNIMA; -.
DR   OrthoDB; 259071at2; -.
DR   Proteomes; UP000002524; Chromosome I.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IBA:GO_Central.
DR   GO; GO:0051117; F:ATPase binding; IBA:GO_Central.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0007035; P:vacuolar acidification; IBA:GO_Central.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR040574; V_ATPase_I_N.
DR   PANTHER; PTHR11629; PTHR11629; 2.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   Pfam; PF18670; V_ATPase_I_N; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Hydrogen ion transport; Ion transport; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..690
FT                   /note="V-type ATP synthase subunit I"
FT                   /id="PRO_0000119241"
FT   TRANSMEM        353..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        412..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        484..504
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        518..538
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        550..570
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        587..607
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        621..641
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   690 AA;  75224 MW;  30D7785EFF388EA2 CRC64;
     MISPMQQVVI AVRKRESDNV ITALQDAGVL HLRPIAEGPL STGNLAGQDA QERREDERLL
     ARAESTIAEL GAYRPAPAPL PAQSEWETVV EGAAQPVSHL AKRRQELQSD LEVDRTYGDA
     VRALARMVGT LDRSRRVALV PFLIGATENL GELDGALRES LGDRYTVASE VVGANRVGVI
     ATLSADRDAA RAALSKARLG ELRLPGRFDT MPLGAAADEL GRVRQGGDDM QRALNAERDR
     LAQQHGPALY AVRDALKDRV AVHDVRAVSA RGKYSLAMQG YVPADRIPAL QSTLSRFGDA
     VSYEVFPVDE HHDQDVPVEL KNSGYVTPFQ NTVMGLMSLP KYGSFDPTWV VALFVPLFFG
     IIMADIGYGL LFLAFGMWLL GKARRNEGWD LSLFGAYLPP ATLRDLGFVT NVMAGWTILW
     GFLTGEFFGT LFEHLGVFYM NNDLLNRLWG WTGVHWGAHA AEGGHSTGLL PIVFPRLDTE
     NFGNIALVFA LCFGILQVLW GWGIRVQQGL KHNDQAHVWE GLAMFGGVGA LILLGFISKA
     GADFGALSNF GDWRVLLMIL GFVLFIVGYL RVAKQFPLLP VELVSQGGSV VSYARIFAVG
     LVSAILAKLC TDLGWSLSQQ IGFLGIILGI VIGALLHFFV LALTLIGHIL QPIRLHMVEF
     LNPTGFNNET SPRYAPLRRL SPASDAGQVK