ID   VATI_METJA              Reviewed;         695 AA.
AC   Q57675;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 123.
DE   RecName: Full=V-type ATP synthase subunit I;
DE   AltName: Full=V-ATPase subunit I;
GN   Name=atpI; OrderedLocusNames=MJ0222;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- FUNCTION: Produces ATP from ADP in the presence of a proton gradient
CC       across the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L77117; AAB98208.1; -; Genomic_DNA.
DR   PIR; G64327; G64327.
DR   AlphaFoldDB; Q57675; -.
DR   SMR; Q57675; -.
DR   STRING; 243232.MJ_0222; -.
DR   EnsemblBacteria; AAB98208; AAB98208; MJ_0222.
DR   KEGG; mja:MJ_0222; -.
DR   eggNOG; arCOG04138; Archaea.
DR   HOGENOM; CLU_025558_1_0_2; -.
DR   InParanoid; Q57675; -.
DR   OMA; MAVNIMA; -.
DR   PhylomeDB; Q57675; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IBA:GO_Central.
DR   GO; GO:0051117; F:ATPase binding; IBA:GO_Central.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0007035; P:vacuolar acidification; IBA:GO_Central.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 2.
DR   Pfam; PF01496; V_ATPase_I; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Hydrogen ion transport; Ion transport; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..695
FT                   /note="V-type ATP synthase subunit I"
FT                   /id="PRO_0000119229"
FT   TRANSMEM        392..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        425..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        497..517
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        534..554
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        556..576
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        605..625
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        627..647
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   695 AA;  76954 MW;  F03E5CEBEE29D53D CRC64;
     MILVRPVRMK KLKAVILDEK IDNVVRSLHE EGIVELCDLS EKLEDLEWKT LLSPSSSADY
     VRNVTSLMIK AGRILDMFSS VSQKETSIKD ILNPKPVEKK KVSFNSYQEV IDYAEKVLNE
     ISKEVDGPAE RLSELDNKKS KLLQLKEQIS YLKGLEFDLK YLGSGEYVFI GAGSVPKEKL
     GELKAELDKV ADGYIGIFSG SEFEKDKKIR VPIVFVTLKE KLENVLSEIR KFEFERYDIS
     DVEGTPSEAL SKIESELKAI ESERNSLIEK LKALAQKWEK ELLAVYELLS IEKARGDAYS
     QFGKTDRTYY IEAWVPARDA EKAKSLIENS ADGFAFVEIT EPDEPEEKIP VLLDNPKVIK
     PFEMLTEMYA LPKYNEVDPT LLLVPGFLLF YGIMLTDAVY GLLLTIIGLF IWKKIGKVSE
     GANKLGYILT LAGISTVIMG IITGGYLGDF TYEFFGFDVT KTPLALVNPL GESYYINNNN
     PLFTLGSISV TNGPMAILVF SIFVGLIHLL IGLFVGFKEN VKRGNMGDAF INQGVWILLI
     LSIFVGIGLM FAGANTMIAG GIIGIFVVLA ILASMYKGYK SGGVMEAILG AMDVTGFLGN
     VLSYARLLAL CLATGGLAMA VNIMAKLVGE SIPVIGIIVA IIILLVGHTF NFVMNGLGAF
     IHSLRLHYVE FFSQFYEGGG KKFSPFKANR EYTTA