ID   VATI_METMA              Reviewed;         649 AA.
AC   O59659;
DT   24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   26-JUL-2002, sequence version 2.
DT   25-MAY-2022, entry version 138.
DE   RecName: Full=V-type ATP synthase subunit I;
DE   AltName: Full=V-ATPase subunit I;
GN   Name=atpI; Synonyms=ahaI; OrderedLocusNames=MM_0785;
OS   Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
OS   11833 / OCM 88) (Methanosarcina frisia).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=192952;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88;
RA   Ruppert C., Wimmers S., Mueller V.;
RL   Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88;
RX   PubMed=12125824;
RA   Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A.,
RA   Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C.,
RA   Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S.,
RA   Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.-P., Gunsalus R.P.,
RA   Fritz H.-J., Gottschalk G.;
RT   "The genome of Methanosarcina mazei: evidence for lateral gene transfer
RT   between Bacteria and Archaea.";
RL   J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
CC   -!- FUNCTION: Produces ATP from ADP in the presence of a proton gradient
CC       across the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAM30481.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; U47274; AAC06381.1; -; Genomic_DNA.
DR   EMBL; AE008384; AAM30481.1; ALT_INIT; Genomic_DNA.
DR   PIR; T45102; T45102.
DR   AlphaFoldDB; O59659; -.
DR   SMR; O59659; -.
DR   STRING; 192952.MM_0785; -.
DR   EnsemblBacteria; AAM30481; AAM30481; MM_0785.
DR   KEGG; mma:MM_0785; -.
DR   PATRIC; fig|192952.21.peg.933; -.
DR   eggNOG; arCOG04138; Archaea.
DR   HOGENOM; CLU_025558_2_1_2; -.
DR   OMA; MLRPERM; -.
DR   Proteomes; UP000000595; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 2.
DR   Pfam; PF01496; V_ATPase_I; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Hydrogen ion transport; Ion transport; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..649
FT                   /note="V-type ATP synthase subunit I"
FT                   /id="PRO_0000119230"
FT   TRANSMEM        348..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        391..411
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        422..442
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        458..478
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        498..518
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        519..539
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        558..578
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        592..612
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        594
FT                   /note="A -> R (in Ref. 1; AAC06381)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   649 AA;  71964 MW;  5C1D02E67B85CAE4 CRC64;
     MSRPKEMTRA VIVGHKSILE ETIDALHDIN LFHIEDFVED ESGFKISKPF KNGEEVSKKL
     VKIRSIANYL GIESKKPVVQ KSDAVLRELD TKLNELDRTI SAKTETISQL ENELKDLDAQ
     KREILPYLSI NLDFEYYRGY ESLKVFAGTV KGSLEESQIS SITKAYELYY DPQSKAVVLF
     VAKNDADKVY ELLQGLGFKE LRVPERGGVP SELLRFIEQK EAEVTRRIES LKGEIESLKV
     KYADFILASD EVLSIESQKA ELPLRIATSA NAFIIDGWTA TEDFDKIVSV VNSATNGKAY
     VTSLELHHEE EEHAPVKYNN SKVVAPMQEI MDLYSRPKYT ELDPSSAIFI TFPLIYGMIL
     GDIGYAIILG SLALAIKKLV KSDAVKPLMN ILIYCQIWTI IFGVLYGEFL GFSLASSHTA
     HGMAAGLIPG WETITLFESI GGEEFTFPIH RSHMVMTMIA ISVLVGLIHL NLGFLFGFSN
     IARHHGIKHA VLEKGSWIII ELGVLVAVLG YFGGIQVFTY AGALILVIGV VMLTMGEGIK
     GPIELPSLMG NALSYARIIA VGLSSIYIAG TVNDIAFEMI WPDHSQIGAA AIAAIIVFIL
     GHGLNTILSI IAPGLHALRL QYVEFFGKFY EGGGRKFNPF GYIRKYTEE