ID   VATI_PYRAB              Reviewed;         659 AA.
AC   Q9UXU2; G8ZKU9;
DT   24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 117.
DE   RecName: Full=V-type ATP synthase subunit I;
DE   AltName: Full=V-ATPase subunit I;
GN   Name=atpI; OrderedLocusNames=PYRAB17660; ORFNames=PAB1180;
OS   Pyrococcus abyssi (strain GE5 / Orsay).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=272844;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GE5 / Orsay;
RX   PubMed=12622808; DOI=10.1046/j.1365-2958.2003.03381.x;
RA   Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O.,
RA   Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J.,
RA   Weissenbach J., Zivanovic Y., Forterre P.;
RT   "An integrated analysis of the genome of the hyperthermophilic archaeon
RT   Pyrococcus abyssi.";
RL   Mol. Microbiol. 47:1495-1512(2003).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=GE5 / Orsay;
RX   PubMed=22057919; DOI=10.1007/s00284-011-0035-x;
RA   Gao J., Wang J.;
RT   "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and
RT   Pyrococcus furiosus DSM 3638.";
RL   Curr. Microbiol. 64:118-129(2012).
CC   -!- FUNCTION: Produces ATP from ADP in the presence of a proton gradient
CC       across the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000305}.
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DR   EMBL; AJ248288; CAB50671.1; -; Genomic_DNA.
DR   EMBL; HE613800; CCE71240.1; -; Genomic_DNA.
DR   PIR; A75029; A75029.
DR   RefSeq; WP_010868885.1; NC_000868.1.
DR   AlphaFoldDB; Q9UXU2; -.
DR   SMR; Q9UXU2; -.
DR   STRING; 272844.PAB1180; -.
DR   EnsemblBacteria; CAB50671; CAB50671; PAB1180.
DR   GeneID; 1496069; -.
DR   KEGG; pab:PAB1180; -.
DR   PATRIC; fig|272844.11.peg.1885; -.
DR   eggNOG; arCOG04138; Archaea.
DR   HOGENOM; CLU_025558_1_0_2; -.
DR   OMA; MAVNIMA; -.
DR   OrthoDB; 14889at2157; -.
DR   PhylomeDB; Q9UXU2; -.
DR   Proteomes; UP000000810; Chromosome.
DR   Proteomes; UP000009139; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 2.
DR   Pfam; PF01496; V_ATPase_I; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Hydrogen ion transport; Ion transport; Membrane;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..659
FT                   /note="V-type ATP synthase subunit I"
FT                   /id="PRO_0000119232"
FT   TRANSMEM        376..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        415..435
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        460..480
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        489..509
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        513..533
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        542..562
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        566..586
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        590..610
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   659 AA;  74289 MW;  DED5A21A8D58D740 CRC64;
     MFKPEEIVKV EIITLARFRD TLLTYLHEMG VAQLDEVPIE GIQRDTPNEF YRKATSYSIT
     LSRLIDTVKH YLPPRKGGIK EFIFPEEKKK RKYKYRGIEE LIKDVEKFLG EAEPKIREVE
     SEVSRLNNEI SALKDSLNAL ELLSSLNIEI ENLRGRSFLS VEVGLVDREK VENLIKELEE
     IAEGRVFTLR KDLAAKSLLV VVSLRKDSGK VISLLAKYGF EKIEIPEGEG LPKDLIPKYI
     ERIKGKEKEL EDVKLKGREI AEKYYEDLVF YKELMDNERE KSNFLSYLVR TEMTFGLLAW
     VPKKDVEKVV EGVKRITNGI AYIEVREPSE EEIENVPVKL KNPEFISHFE MLTEMYGVPK
     YNEIDPTPIL AFTYSFFFGF MLTDFVYGLL LGVISALLVK GHSKLKDGTW KFAKIMLWAS
     AFTMVLGILF GSYCGNLLDM AGVKVPRLLD TMSEALTVLV MALAIGLGHL FTGYILGFIV
     NWKNGDKRAA ILEQLPWVFI IIGITLFALS SKLGIPQIAF KAVFGVGLAL FVVGEIVNNK
     GMAVLLTISD FFGFIGNWLS YARLMALALA TSGIALVINI IANMVWGLKI GPIPLGILIG
     IVILIGGHIF STAINALGAF VHALRLHYVE FFGTFYSGEG RKFEPFAAKR EVSELEIES