ID   VATI_THEAC              Reviewed;         637 AA.
AC   Q9HM61;
DT   24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2001, sequence version 1.
DT   25-MAY-2022, entry version 107.
DE   RecName: Full=V-type ATP synthase subunit I;
DE   AltName: Full=V-ATPase subunit I;
GN   Name=atpI; OrderedLocusNames=Ta0008;
OS   Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC
OS   15155 / AMRC-C165).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC   Thermoplasmataceae; Thermoplasma.
OX   NCBI_TaxID=273075;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165;
RX   PubMed=11029001; DOI=10.1038/35035069;
RA   Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C.,
RA   Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.;
RT   "The genome sequence of the thermoacidophilic scavenger Thermoplasma
RT   acidophilum.";
RL   Nature 407:508-513(2000).
CC   -!- FUNCTION: Produces ATP from ADP in the presence of a proton gradient
CC       across the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL445063; CAC11157.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9HM61; -.
DR   SMR; Q9HM61; -.
DR   STRING; 273075.Ta0008; -.
DR   EnsemblBacteria; CAC11157; CAC11157; CAC11157.
DR   KEGG; tac:Ta0008; -.
DR   eggNOG; arCOG04138; Archaea.
DR   HOGENOM; CLU_025558_2_1_2; -.
DR   OMA; MAVNIMA; -.
DR   Proteomes; UP000001024; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 2.
DR   Pfam; PF01496; V_ATPase_I; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Hydrogen ion transport; Ion transport; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..637
FT                   /note="V-type ATP synthase subunit I"
FT                   /id="PRO_0000119236"
FT   TRANSMEM        342..362
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        403..423
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        436..456
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        471..491
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        498..518
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        541..561
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        568..588
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   637 AA;  71573 MW;  4B48B1DD7D82486A CRC64;
     MEKIRIIAPY SYRDPVISAL HDLGVMQIEE MREDVDRLLS PAKASEQAKT VMDYLQKFRG
     YENILPKRPV RTRAKFTSLA DILNEASKIN IDDDIRIAVN RENDIAAAMK DIDSRLSALE
     YMKGYDFDVS IFNGKHFESY IIPDKNVDIK AFSSLNAEIV PLKNAFIITV AEDRTQDLSR
     IANSIGARLI HIPDLKGKPD DVIAMLNDER AKLDQAMQEI RKHLGDLSDK YYEKIAQIRE
     ALEIEAKKID VEDKLKGTEY TFAVEGWIPS DSFGRVSDAI NRVTGNSCII STVKTNEMPP
     TLLRNPRRIS LFEFFIKFYS LPEGTEYDPT LIFALVFPVF FGLMVGDWGY GLAILLISLF
     IIHRVDHPPA KSHIPRVISR FVLMIMSPQS LKTLAKALIP SSIVAIIAGL LFNEFFGFAI
     LPFTVFHVYA VLPKLMLIAG YIGLGMVVFG FILGFIEDLW MKDVKGAMDR LGWLFFAVGI
     ATIGLNLIHH DLTFSVSTGI SNLIAVALIV IGIPLIAIKE KSQGFIEMPS IISHILSYLR
     LVGILIASVV IAEIIDLVFM KSIVSHSIGL AIAGVVILIF GQMFNLILAV FEPGIQGARL
     IYVEFFSKFY HGNGRMFRPF RSQRKYTEDG LDFDKAR