ID   VA_PHOKE                Reviewed;         147 AA.
AC   P85860;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   25-MAY-2022, entry version 42.
DE   RecName: Full=CRISP-1;
DE   AltName: Full=Cysteine-rich venom protein;
DE            Short=CRVP;
DE   AltName: Full=Venom allergen;
DE   Flags: Fragments;
OS   Phoneutria keyserlingi (Brazilian wandering spider) (Ctenus keyserlingii).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC   Araneomorphae; Entelegynae; Lycosoidea; Ctenidae; Phoneutria.
OX   NCBI_TaxID=272754;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RC   TISSUE=Venom {ECO:0000269|Ref.1};
RA   Richardson M., Souza I.A., Rezende F.F., Borges M.H., Sousa A.,
RA   Cordeiro M.N.;
RT   "Allergenic protein in venom of spider Phoneutria keyserlingi.";
RL   Submitted (MAY-2008) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000269|Ref.1}.
CC   -!- ALLERGEN: Causes an allergic reaction in human.
CC       {ECO:0000250|UniProtKB:P35779}.
CC   -!- SIMILARITY: Belongs to the CRISP family. {ECO:0000255}.
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DR   AlphaFoldDB; P85860; -.
DR   ArachnoServer; AS000013; CRISP-1-Phoneutria keyserlingi.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.33.10; -; 1.
DR   InterPro; IPR035940; CAP_sf.
DR   SUPFAM; SSF55797; SSF55797; 1.
PE   1: Evidence at protein level;
KW   Allergen; Direct protein sequencing; Secreted.
FT   CHAIN           1..>147
FT                   /note="CRISP-1"
FT                   /id="PRO_0000343534"
FT   NON_CONS        63..64
FT                   /evidence="ECO:0000303|Ref.1"
FT   NON_CONS        71..72
FT                   /evidence="ECO:0000303|Ref.1"
FT   NON_CONS        79..80
FT                   /evidence="ECO:0000303|Ref.1"
FT   NON_CONS        120..121
FT                   /evidence="ECO:0000303|Ref.1"
FT   NON_CONS        133..134
FT                   /evidence="ECO:0000303|Ref.1"
FT   NON_TER         147
FT                   /evidence="ECO:0000303|Ref.1"
SQ   SEQUENCE   147 AA;  16592 MW;  B9220691ABDC985B CRC64;
     GLCPDKYKRY SLQHSFCLPT CVSCAFYSKD VRYWLKNYIL YQHNNLRNVV ASGRSYGVDH
     VPRICLTVVT RIGCGYLFRK YTNVICNYGP RGNVEGEEIY KGGDICSACP ANTCCGDGCK
     YHGLCKFGEP NLPEIFYCGF NGESDCR