ID   VB05_VACC8              Reviewed;          92 AA.
AC   P24284;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   12-AUG-2020, entry version 52.
DE   RecName: Full=Truncated plaque-size/host range protein;
DE   AltName: Full=Protein B5;
DE   Flags: Precursor;
GN   Name=PS/HR; ORFNames=B5R;
OS   Vaccinia virus (strain LC16m8) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10248;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1994573; DOI=10.1016/0042-6822(91)90480-y;
RA   Takahashi-Nishimaki F., Funahashi S., Miki K., Hashizume S., Sugimoto M.;
RT   "Regulation of plaque size and host range by a vaccinia virus gene related
RT   to complement system proteins.";
RL   Virology 181:158-164(1991).
CC   -!- FUNCTION: Regulation of plaque size and host range. In this strain the
CC       truncated ps/hr protein is probably not functional.
CC   -!- MISCELLANEOUS: The small-plaque-forming LC16m8 strain is not able to
CC       proliferate in vero (YTV) cells.
CC   -!- SIMILARITY: Belongs to the receptors of complement activation (RCA)
CC       family. {ECO:0000305}.
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DR   EMBL; M55435; AAA48317.1; -; Genomic_DNA.
DR   SMR; P24284; -.
DR   CDD; cd00033; CCP; 1.
DR   InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR   InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR   Pfam; PF00084; Sushi; 1.
DR   SMART; SM00032; CCP; 1.
DR   SUPFAM; SSF57535; SSF57535; 1.
DR   PROSITE; PS50923; SUSHI; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Signal; Sushi.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..92
FT                   /note="Truncated plaque-size/host range protein"
FT                   /id="PRO_0000006022"
FT   DOMAIN          19..74
FT                   /note="Sushi"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00302"
FT   DISULFID        21..61
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00302"
FT   DISULFID        48..72
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00302"
SQ   SEQUENCE   92 AA;  10418 MW;  766DE77F61432AF2 CRC64;
     MKTISVVTLL CVLPAVVYST CTVPTMNNAK LTSTETSFND KQKVTFTCDQ GYHSLDPNAV
     CETDKWKYEN PCKKMCTVSD YVSELYDKPL YK