ID   VB18_VACCC              Reviewed;         574 AA.
AC   P21076;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   23-FEB-2022, entry version 89.
DE   RecName: Full=Ankyrin repeat protein B18;
GN   ORFNames=B18R;
OS   Vaccinia virus (strain Copenhagen) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10249;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=2219722; DOI=10.1016/0042-6822(90)90294-2;
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "The complete DNA sequence of vaccinia virus.";
RL   Virology 179:247-266(1990).
RN   [2]
RP   COMPLETE GENOME.
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "Appendix to 'The complete DNA sequence of vaccinia virus'.";
RL   Virology 179:517-563(1990).
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DR   EMBL; M35027; AAA48217.1; -; Genomic_DNA.
DR   PIR; H42527; H42527.
DR   SMR; P21076; -.
DR   Proteomes; UP000008269; Genome.
DR   Gene3D; 1.25.40.20; -; 3.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR018272; PRANC_domain.
DR   Pfam; PF00023; Ank; 2.
DR   Pfam; PF13606; Ank_3; 1.
DR   Pfam; PF09372; PRANC; 1.
DR   SMART; SM00248; ANK; 6.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   4: Predicted;
KW   ANK repeat; Reference proteome; Repeat.
FT   CHAIN           1..574
FT                   /note="Ankyrin repeat protein B18"
FT                   /id="PRO_0000067089"
FT   REPEAT          56..87
FT                   /note="ANK 1"
FT   REPEAT          135..164
FT                   /note="ANK 2"
FT   REPEAT          167..213
FT                   /note="ANK 3"
FT   REPEAT          217..249
FT                   /note="ANK 4"
FT   REPEAT          253..285
FT                   /note="ANK 5"
FT   REPEAT          327..356
FT                   /note="ANK 6"
FT   DOMAIN          541..574
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
SQ   SEQUENCE   574 AA;  68070 MW;  4173B1452CEB197B CRC64;
     MSRRLIYVLN INRKSTHKIQ ENEIYTYFSH CNIDHTSTEL DFVVKNYDLN RRQHVTGYTA
     LHCYLYNNYF TNDVLKILLN HDVNVTMKTS SGRMPVYILL TRCCNISHDV VIDMIDKDKN
     HLSHRDYSNL LLEYIKSRYM LLKEEDIDEN IVSTLLDKGI DPNFKQDGYT ALHYYYLCLA
     HVYKPGECRK PITIKKAKRI ISLFIQHGAN LNALDNCGNT PFHLYLSIEM CNNIHMTKML
     LTFNPNFKIC NNHGLTPILC YITSDYIQHD ILVMLIHHYE TNVGEMPIDE RRMIVFEFIK
     TYSTRPADSI TYLMNRFKNI NIYTRYEGKT LLHVACEYNN TQVIDYLIRI NGDINALTDN
     NKHATQLIID NKENSPYTIN CLLYILRYIV DKNVIRSLVD QLPSLPIFDI KSFEKFISYC
     ILLDDTFYDR HVKNRDSKTY RYAFSKYMSF DKYDGIITKC HDETMLLKLS TVLDTTLYAV
     LRCHNSRKLR RYLTELKKYN NDKSFKIYSN IMNERYLNVY YKDMYVSKVY DKLFPVFTDK
     NCLLTLLPSE IIYEILYMLT INDLYNISYP PTKV