ID   VC02_VACCT              Reviewed;         512 AA.
AC   Q9JFG1;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Kelch repeat protein C2;
GN   ORFNames=TC2L;
OS   Vaccinia virus (strain Tian Tan) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10253;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Jin Q., Hou Y.D., Cheng N.H., Yao E.M., Cheng S.X., Yang X.K., Jing D.Y.,
RA   Yu W.H., Yuan J.S., Ma X.J.;
RT   "Complete genomic sequence of vaccinia virus (Tian Tan strain).";
RL   Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the poxviruses Kelch family. {ECO:0000305}.
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DR   EMBL; AF095689; AAF33878.1; -; Genomic_DNA.
DR   SMR; Q9JFG1; -.
DR   Proteomes; UP000163220; Genome.
DR   Gene3D; 2.120.10.80; -; 1.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 3.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 3.
DR   SUPFAM; SSF117281; SSF117281; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   3: Inferred from homology;
KW   Early protein; Kelch repeat; Repeat.
FT   CHAIN           1..512
FT                   /note="Kelch repeat protein C2"
FT                   /id="PRO_0000119158"
FT   DOMAIN          2..67
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT   REPEAT          216..261
FT                   /note="Kelch 1"
FT   REPEAT          262..307
FT                   /note="Kelch 2"
FT   REPEAT          309..354
FT                   /note="Kelch 3"
FT   REPEAT          356..403
FT                   /note="Kelch 4"
FT   REPEAT          405..449
FT                   /note="Kelch 5"
FT   REPEAT          452..498
FT                   /note="Kelch 6"
SQ   SEQUENCE   512 AA;  59213 MW;  094DBECBDBED3410 CRC64;
     MESVIFSING EIIQVNKEII TASPYNFFKR IQDHHLKDEA IILNGINYHA FESLLDYIRW
     KKINITINNV EMILVAAIII DVPPVVDLCV KTMIHNINST NCIRMFNFSK QYGIKKLYNA
     SMSEIINNIT AVTSDPEFGK LSKDELTTIL SHEDVNVNHE DVTAMILLKW IHKNPNDVDI
     INILHPKFMT NTMRNAISLL GLTISKSTKP VTRNGIKHNI VVIKNSDYIS TITHYSPRTE
     YWTIVGNTDR QFYNANVLHN CLYIIGGMIN NRHVYSVSRV DLETKKWKTV TNMSSLKSEV
     STCVNNGKLY VIGGLEFSIS TGVAEYLKHG TSKWIRLPNL ITPRYSGASV FVNDDIYVMG
     GVYTTYEKYV VLNDVECFTK NRWIKKSPMP RHHSIVYAVE YDGDIYVITG ITHETRNYLY
     KYIVKEDKWI ELYMYFNHVG KMFVCSCGDY ILIIADAKYE YYPKSNTWNL FDMSTRNIEY
     YDMFTKDETP KCNVTHKSLP SFLSNCEKQF LQ