ID   VC04_SWPVK              Reviewed;         530 AA.
AC   P32228;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   23-FEB-2022, entry version 77.
DE   RecName: Full=Protein C4;
GN   ORFNames=C4L;
OS   Swinepox virus (strain Kasza) (SWPV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Suipoxvirus.
OX   NCBI_TaxID=10277;
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=8249275; DOI=10.1006/viro.1993.1625;
RA   Massung R.F., Jayarama V., Moyer R.W.;
RT   "DNA sequence analysis of conserved and unique regions of swinepox virus:
RT   identification of genetic elements supporting phenotypic observations
RT   including a novel G protein-coupled receptor homologue.";
RL   Virology 197:511-528(1993).
CC   -!- SIMILARITY: Belongs to the poxviruses Kelch family. {ECO:0000305}.
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DR   EMBL; L22013; AAC37867.1; -; Unassigned_RNA.
DR   SMR; P32228; -.
DR   Gene3D; 2.120.10.80; -; 2.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR024182; Vaccinia_A55R.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 3.
DR   PIRSF; PIRSF003716; VAC_F3L; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 4.
DR   SUPFAM; SSF50965; SSF50965; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   3: Inferred from homology;
KW   Kelch repeat; Repeat.
FT   CHAIN           1..530
FT                   /note="Protein C4"
FT                   /id="PRO_0000119168"
FT   DOMAIN          18..86
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT   REPEAT          239..284
FT                   /note="Kelch 1"
FT   REPEAT          285..331
FT                   /note="Kelch 2"
FT   REPEAT          333..379
FT                   /note="Kelch 3"
FT   REPEAT          381..434
FT                   /note="Kelch 4"
FT   REPEAT          435..486
FT                   /note="Kelch 5"
FT   REPEAT          487..529
FT                   /note="Kelch 6"
SQ   SEQUENCE   530 AA;  62639 MW;  31897A2422263F11 CRC64;
     MNSLLLRLHD FFKHGIMCDI KIVSIENNKT ISAHRLILSM YSKYFYNIFN SDFIDKNNDE
     IYICADYDIL YIILEFMYTG NIVLTKDNIE LVIQVCDYLC IDSLIKICEE YICGIIDETN
     CIHLLNFSDT YNLQRLREMS KWYLPKIINN NKLVVELDID DMILIIKEIK YIACEYIVKK
     IILNWIVHKD ERIIYTKKLM KHINDQDHYT SLSDIELYNN IRERIYDNKE HDVDISHNFI
     IMVGGKKIFN ITAFNPLSNK KHIIDRYDDM FGCKTHFSVV YLNSILYIIG GKKRGYFTKE
     VLSYNIKNKL WCYEPELNYF RYDTSVCVSN GMIYSIGGKD TNGYMTNIVE FWKPEWKSWY
     DGQHLCYPRC YMSLVDYNNE VYTIGGLKTS ITDEFNIEMI VSDDAVEKLT DHSWMKLKQF
     PIAKSGISSI VYNDFIYCIG GRIDTPHISI EHTNDVYIYS SRDDCWKYLS NTNVKRSFCL
     SCVFNNELYI IGGYNTNSVE KYNKLKNTWK RLNDIPKFEE CVNEASAIYL