VDAC5_ARATH
ID VDAC5_ARATH Reviewed; 226 AA.
AC Q9M2W6;
DT 14-DEC-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Putative mitochondrial outer membrane protein porin 5;
DE AltName: Full=Voltage-dependent anion-selective channel protein 5;
DE Short=AtVDAC5;
DE Short=VDAC-5;
GN Name=VDAC5; OrderedLocusNames=At3g49920; ORFNames=F3A4.1, T16K5.270;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=21705391; DOI=10.1093/jxb/err113;
RA Tateda C., Watanabe K., Kusano T., Takahashi Y.;
RT "Molecular and genetic characterization of the gene family encoding the
RT voltage-dependent anion channel in Arabidopsis.";
RL J. Exp. Bot. 62:4773-4785(2011).
CC -!- FUNCTION: Putative channel that allows diffusion of small hydrophilic
CC molecules through membranes. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9M2W6-1; Sequence=Displayed;
CC -!- DOMAIN: Consists mainly of membrane-spanning sided beta-sheets.
CC -!- SIMILARITY: Belongs to the eukaryotic mitochondrial porin (TC 1.B.8.1)
CC family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR EMBL; AL132965; CAB66930.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78606.1; -; Genomic_DNA.
DR PIR; T46058; T46058.
DR RefSeq; NP_190561.1; NM_114852.1. [Q9M2W6-1]
DR AlphaFoldDB; Q9M2W6; -.
DR SMR; Q9M2W6; -.
DR BioGRID; 9472; 5.
DR STRING; 3702.AT3G49920.1; -.
DR PaxDb; Q9M2W6; -.
DR PRIDE; Q9M2W6; -.
DR EnsemblPlants; AT3G49920.1; AT3G49920.1; AT3G49920. [Q9M2W6-1]
DR GeneID; 824154; -.
DR Gramene; AT3G49920.1; AT3G49920.1; AT3G49920. [Q9M2W6-1]
DR KEGG; ath:AT3G49920; -.
DR Araport; AT3G49920; -.
DR TAIR; locus:2097425; AT3G49920.
DR eggNOG; KOG3126; Eukaryota.
DR HOGENOM; CLU_069937_0_0_1; -.
DR InParanoid; Q9M2W6; -.
DR OrthoDB; 938262at2759; -.
DR PhylomeDB; Q9M2W6; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9M2W6; baseline and differential.
DR Genevisible; Q9M2W6; AT.
DR GO; GO:0005741; C:mitochondrial outer membrane; IBA:GO_Central.
DR GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR GO; GO:0008308; F:voltage-gated anion channel activity; IBA:GO_Central.
DR CDD; cd07306; Porin3_VDAC; 1.
DR Gene3D; 2.40.160.10; -; 2.
DR InterPro; IPR023614; Porin_dom_sf.
DR InterPro; IPR001925; Porin_Euk.
DR InterPro; IPR027246; Porin_Euk/Tom40.
DR PANTHER; PTHR11743; PTHR11743; 2.
DR Pfam; PF01459; Porin_3; 2.
PE 5: Uncertain;
KW Alternative splicing; Ion transport; Membrane; Mitochondrion;
KW Mitochondrion outer membrane; Porin; Reference proteome; Transmembrane;
KW Transmembrane beta strand; Transport.
FT CHAIN 1..226
FT /note="Putative mitochondrial outer membrane protein porin
FT 5"
FT /id="PRO_0000414083"
SQ SEQUENCE 226 AA; 24631 MW; 52AE951CB312855E CRC64;
MSKGPGLFAD IGKYAKDLLT RDYSTDQKFS ISTNSVSGVA LTSTALKNGV LHAANVATQY
KYRNTFFDVK IDTDFNVKSL VYPMNKFVSI DHNTLTGYDT TSRTFTKYNV GVSVTKPDQC
VSIILGDKGD SIKASYVYYL DESTRSATVG EVIRKISTNE TTVTVGGLYA VDHLTNVKAK
LNSNGKFGAL LQHEGLPKSI VTISGEIDTK TLDKYPRLGL SLSLKP
