ID   VDAC_DORPE              Reviewed;          27 AA.
AC   P82945;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Voltage-dependent anion-selective channel protein;
DE            Short=VDAC;
DE   AltName: Full=Outer mitochondrial membrane protein porin;
DE   Flags: Fragment;
OS   Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC   Coleoidea; Decapodiformes; Teuthida; Myopsina; Loliginidae; Doryteuthis.
OX   NCBI_TaxID=1051067;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, AND TISSUE SPECIFICITY.
RC   TISSUE=Retinal photoreceptor {ECO:0000269|Ref.1};
RA   Mohammed M., Ahmed T., Findlay J.B.C.;
RT   "Purification and identification of porin in squid photoreceptor
RT   membranes.";
RL   Submitted (JAN-2001) to UniProtKB.
CC   -!- FUNCTION: Forms a channel through the cell membrane that allows
CC       diffusion of small hydrophilic molecules. {ECO:0000269|Ref.1}.
CC   -!- SUBUNIT: Interacts with hexokinases. {ECO:0000250|UniProtKB:Q94920}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Photoreceptors. {ECO:0000269|Ref.1}.
CC   -!- DOMAIN: Consists mainly of membrane-spanning sided beta-sheets.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the eukaryotic mitochondrial porin family.
CC       {ECO:0000255}.
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DR   AlphaFoldDB; P82945; -.
DR   SMR; P82945; -.
DR   GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR023614; Porin_dom_sf.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Ion transport; Membrane; Mitochondrion;
KW   Mitochondrion outer membrane; Porin; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   CHAIN           1..>27
FT                   /note="Voltage-dependent anion-selective channel protein"
FT                   /id="PRO_0000263033"
FT   NON_TER         27
FT                   /evidence="ECO:0000303|Ref.1"
SQ   SEQUENCE   27 AA;  2963 MW;  50508BB635C5E4E5 CRC64;
     VPPVYADLGK GARDLFSKGY NYGFSKL