ID   VDAC_SCHPO              Reviewed;         282 AA.
AC   Q9P544;
DT   01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Probable mitochondrial outer membrane protein porin;
GN   ORFNames=SPAC1635.01;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Forms a channel through the cell membrane that allows
CC       diffusion of small hydrophilic molecules. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250}.
CC   -!- DOMAIN: Consists mainly of membrane-spanning sided beta-sheets.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eukaryotic mitochondrial porin family.
CC       {ECO:0000305}.
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DR   EMBL; CU329670; CAB92123.1; -; Genomic_DNA.
DR   RefSeq; NP_594661.1; NM_001020090.2.
DR   AlphaFoldDB; Q9P544; -.
DR   SMR; Q9P544; -.
DR   BioGRID; 279200; 6.
DR   STRING; 4896.SPAC1635.01.1; -.
DR   iPTMnet; Q9P544; -.
DR   MaxQB; Q9P544; -.
DR   PaxDb; Q9P544; -.
DR   PRIDE; Q9P544; -.
DR   EnsemblFungi; SPAC1635.01.1; SPAC1635.01.1:pep; SPAC1635.01.
DR   PomBase; SPAC1635.01; -.
DR   VEuPathDB; FungiDB:SPAC1635.01; -.
DR   eggNOG; KOG3126; Eukaryota.
DR   HOGENOM; CLU_044399_1_0_1; -.
DR   InParanoid; Q9P544; -.
DR   OMA; PWSWRLN; -.
DR   PhylomeDB; Q9P544; -.
DR   Reactome; R-SPO-70268; Pyruvate metabolism.
DR   PRO; PR:Q9P544; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005741; C:mitochondrial outer membrane; ISO:PomBase.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0008308; F:voltage-gated anion channel activity; ISO:PomBase.
DR   GO; GO:0098661; P:inorganic anion transmembrane transport; ISO:PomBase.
DR   GO; GO:1990542; P:mitochondrial transmembrane transport; ISO:PomBase.
DR   CDD; cd07306; Porin3_VDAC; 1.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   InterPro; IPR001925; Porin_Euk.
DR   InterPro; IPR027246; Porin_Euk/Tom40.
DR   PANTHER; PTHR11743; PTHR11743; 1.
DR   Pfam; PF01459; Porin_3; 1.
DR   PRINTS; PR00185; EUKARYTPORIN.
PE   3: Inferred from homology;
KW   Ion transport; Membrane; Mitochondrion; Mitochondrion outer membrane;
KW   Porin; Reference proteome; Transmembrane; Transmembrane beta strand;
KW   Transport.
FT   CHAIN           1..282
FT                   /note="Probable mitochondrial outer membrane protein porin"
FT                   /id="PRO_0000050523"
SQ   SEQUENCE   282 AA;  29653 MW;  2D91FE5D156DFB1B CRC64;
     MAPPAYAAIN KLCNDLLQRD FPVGATLLSV RTTAPNGVVF NVSGNQDAKG VISGKLETSF
     NDKANGLTIS QGWTTANVLE SKVGLSEQFA PGLHLNVNTT FSPATAAKTA ILNLEHQHPL
     IHTHASVNAL ERKFLGDFTV GHEGFLAGAE FGYDVQKGNV SNYAATIGYL ASPLSVALQA
     SNNLSVFRAS YYHRVSSDVE AGGNVTWDAA STANAITLEL ASKYALDKDT FVKGKINSAG
     VATLSYFQTV RPGVTVGLGL QLDTQRLGQP AHKAGLSLAF SA