ID   VE5_BPV2                Reviewed;          44 AA.
AC   P0CK46; P06928;
DT   21-MAR-2012, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2012, sequence version 1.
DT   07-APR-2021, entry version 16.
DE   RecName: Full=Protein E5;
GN   Name=E5;
OS   Bos taurus papillomavirus 2 (Bovine papillomavirus 2).
OC   Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes;
OC   Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae;
OC   Deltapapillomavirus.
OX   NCBI_TaxID=2758382;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Groff D.E., Mitra R., Lancaster W.D.;
RL   Submitted (MAY-1988) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: E5 can induce cellular DNA synthesis. It seems to interact
CC       with a 16 kDa cellular protein. E5 seems to activate the PDGF receptor
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Dimer or monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the papillomaviridae E5 protein family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M20219; AAA66838.1; -; Genomic_DNA.
DR   Proteomes; UP000007612; Genome.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR012555; EPV_E5.
DR   Pfam; PF08135; EPV_E5; 1.
DR   PIRSF; PIRSF003401; EPV_E5; 1.
PE   3: Inferred from homology;
KW   Early protein; Host membrane; Membrane; Oncogene.
FT   CHAIN           1..44
FT                   /note="Protein E5"
FT                   /id="PRO_0000415967"
FT   REGION          32..44
FT                   /note="Cellular DNA synthesis induction"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   44 AA;  5210 MW;  0E278099E06F2956 CRC64;
     MPNLWFLLFL GLVAAMQLLL LLFLLLFFLV YWDHFECSCT GLPF