ID   VEF_GVHA                Reviewed;         902 AA.
AC   P54232;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   29-SEP-2021, entry version 52.
DE   RecName: Full=Viral-enhancing factor;
DE            Short=Enhancin;
DE            Short=VEF;
DE   AltName: Full=104 kDa glycoprotein;
DE   AltName: Full=Synergistic factor;
GN   Name=VEF;
OS   Heliothis armigera granulosis virus (HaGV) (Heliothis armigera
OS   granulovirus).
OC   Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Betabaculovirus;
OC   unclassified Betabaculovirus.
OX   NCBI_TaxID=45440;
OH   NCBI_TaxID=7101; Heliothis.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7595376; DOI=10.1099/0022-1317-76-11-2693;
RA   Roelvink P.W., Corsaro B.G., Granados R.R.;
RT   "Characterization of the Helicoverpa armigera and Pseudaletia unipuncta
RT   granulovirus enhancin genes.";
RL   J. Gen. Virol. 76:2693-2705(1995).
CC   -!- FUNCTION: Involved in disruption of the peritrophic membrane and fusion
CC       of nucleocapsids with midgut cells. {ECO:0000250}.
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DR   EMBL; D28558; BAA05908.1; -; Genomic_DNA.
DR   MEROPS; M60.004; -.
DR   PRIDE; P54232; -.
DR   InterPro; IPR004954; Mucin-bd.
DR   InterPro; IPR031161; Peptidase_M60_dom.
DR   Pfam; PF03272; Mucin_bdg; 1.
DR   Pfam; PF13402; Peptidase_M60; 1.
DR   SMART; SM01276; M60-like; 1.
DR   PROSITE; PS51723; PEPTIDASE_M60; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Late protein.
FT   CHAIN           1..902
FT                   /note="Viral-enhancing factor"
FT                   /id="PRO_0000132865"
FT   DOMAIN          27..330
FT                   /note="Peptidase M60"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01060"
FT   CARBOHYD        73
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        265
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        278
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        339
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        540
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        593
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        594
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        620
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        782
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        840
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   902 AA;  104792 MW;  D8E45BAA5F675FDE CRC64;
     MSYNVIVPTT VLPPWLRIGQ NWIFARHRRT EVGVVLPANT KFRVRADFAK WGITRPVIVR
     LLNNNRNTER EINLTNDQWI EMEHEHECVP FVDWPVGEKN TMAEVHFEID GPHIPLPVYV
     FNTRPVENFK SEYRQSSSGY CFLYLDLVCI LVPPASKNVL LDTDLFELHQ FYNEIINYYD
     DLCGLVEDPY ADTVDSNLPN KAAFVKADGG GPGGAYYGAF WTAPASTNLG EYLRVSPTNW
     MVIHELGHAY DFVFTVNTRL IEIWNNSFCD RIQYTWMNKT KRQQLARIYE NQRPQKEAAI
     QALIDNNVPF DNWDFFEKLS IFAWLYNPQR GLDTLRNINH SYRLHAARNP VTPYPQIWAW
     LMSCGYDNFW LYFNRIGLYP ADFYINEHNK VVHFNLHMRA LALGQSVRYP IKYIITDFDL
     LQKNYDIKQY LESNFDLVIP EELRQTDLVA DVRVVCVIDD PSQIIGEPFS LYDGNERVFE
     STVATDGNMY LVGVGPGVYT LRAPRGKDKR YKLHLAHSPN EPVHPANDHM YLLVTYPYYN
     QTLTYTRYIT SDLAIDAAHL FGTDRLYVAT IYFDALQQTV TVYLNNIRTG RENNTTLYFE
     MEIHNPFIGT SSKFTLLEDN VTMRQGYYKF PAVTFSSIRL HIRDDNRLML VDKYLPAGDT
     LLFMFPNQIV DNNIFPDGSI LTSTYNRIKE QAAFIENHKQ LLYIENELRD SIYLASQFVN
     SDSNEFLKYF PDYFRDPHTF SYLFRFRGLG DFMLLELQIV PILNLASVRV GNHHNGPHSY
     FNTTYLSVEV RDTSGGVVFS YSRLGNEPMT HEHHKFEVFK DYTIHLFIQE PGQRLQLIVN
     KTLDTALPNS QNIYARLTAT QLVVGEQSII ISDDNDFVPP PPRVNCGDQQ IRVVETLKMI
     AF