ID   VELAC_TRIVU             Reviewed;          38 AA.
AC   P85093;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   26-JUN-2007, sequence version 1.
DT   25-MAY-2022, entry version 12.
DE   RecName: Full=Very early lactation protein;
DE            Short=VELP;
DE   Flags: Fragments;
OS   Trichosurus vulpecula (Brush-tailed possum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Metatheria; Diprotodontia; Phalangeridae; Trichosurus.
OX   NCBI_TaxID=9337;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, SUBUNIT, SUBCELLULAR LOCATION, TISSUE SPECIFICITY,
RP   DEVELOPMENTAL STAGE, GLYCOSYLATION, AND VARIANT ILE-8.
RC   TISSUE=Lactating mammary gland {ECO:0000269|Ref.1};
RX   DOI=10.1016/j.cbd.2007.01.002;
RA   Kuy S., Kelly V.C., Smit A.-M., Palmer D.J., Cooper G.J.;
RT   "Proteomic analysis of whey and casein proteins in early milk from the
RT   marsupial Trichosurus vulpecula, the common brushtail possum.";
RL   Comp. Biochem. Physiol. 2D:112-120(2007).
CC   -!- SUBUNIT: Homodimer. {ECO:0000269|Ref.1}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
CC   -!- TISSUE SPECIFICITY: Found in the whey fraction of milk (at protein
CC       level). {ECO:0000269|Ref.1}.
CC   -!- DEVELOPMENTAL STAGE: Expressed predominantly during the first 40 days
CC       of lactation, after which levels decrease sharply. {ECO:0000269|Ref.1}.
CC   -!- PTM: O-glycosylated. Contains sialic acid residues.
CC       {ECO:0000269|Ref.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; P85093; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Glycoprotein; Milk protein; Secreted;
KW   Sialic acid.
FT   CHAIN           1..>38
FT                   /note="Very early lactation protein"
FT                   /id="PRO_0000292881"
FT   VARIANT         8
FT                   /note="V -> I"
FT                   /evidence="ECO:0000269|Ref.1"
FT   UNSURE          21
FT                   /note="I or L"
FT                   /evidence="ECO:0000269|Ref.1"
FT   UNSURE          23
FT                   /note="I or L"
FT                   /evidence="ECO:0000269|Ref.1"
FT   UNSURE          25
FT                   /note="I or L"
FT                   /evidence="ECO:0000269|Ref.1"
FT   UNSURE          32
FT                   /note="I or L"
FT                   /evidence="ECO:0000269|Ref.1"
FT   UNSURE          33
FT                   /note="I or L"
FT                   /evidence="ECO:0000269|Ref.1"
FT   UNSURE          34
FT                   /note="Q or K"
FT                   /evidence="ECO:0000269|Ref.1"
FT   UNSURE          35
FT                   /note="I or L"
FT                   /evidence="ECO:0000269|Ref.1"
FT   NON_CONS        17..18
FT                   /evidence="ECO:0000303|Ref.1"
FT   NON_CONS        27..28
FT                   /evidence="ECO:0000303|Ref.1"
FT   NON_TER         38
FT                   /evidence="ECO:0000303|Ref.1"
SQ   SEQUENCE   38 AA;  4589 MW;  1E4E16678ED4D91A CRC64;
     DVNELNDVEE RRAVVPQVWE IDIMITKHND EIIQIEER