ID   VEL_LACBS               Reviewed;         345 AA.
AC   B0D4E7;
DT   13-APR-2016, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Probable velvet family sexual development regulator LACBIDRAFT_317102 {ECO:0000305};
GN   ORFNames=LACBIDRAFT_317102;
OS   Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver)
OS   (Laccaria laccata var. bicolor).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Tricholomataceae; Laccaria.
OX   NCBI_TaxID=486041;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 / ATCC MYA-4686;
RX   PubMed=18322534; DOI=10.1038/nature06556;
RA   Martin F., Aerts A., Ahren D., Brun A., Danchin E.G.J., Duchaussoy F.,
RA   Gibon J., Kohler A., Lindquist E., Pereda V., Salamov A., Shapiro H.J.,
RA   Wuyts J., Blaudez D., Buee M., Brokstein P., Canbaeck B., Cohen D.,
RA   Courty P.E., Coutinho P.M., Delaruelle C., Detter J.C., Deveau A.,
RA   DiFazio S., Duplessis S., Fraissinet-Tachet L., Lucic E., Frey-Klett P.,
RA   Fourrey C., Feussner I., Gay G., Grimwood J., Hoegger P.J., Jain P.,
RA   Kilaru S., Labbe J., Lin Y.C., Legue V., Le Tacon F., Marmeisse R.,
RA   Melayah D., Montanini B., Muratet M., Nehls U., Niculita-Hirzel H.,
RA   Oudot-Le Secq M.P., Peter M., Quesneville H., Rajashekar B., Reich M.,
RA   Rouhier N., Schmutz J., Yin T., Chalot M., Henrissat B., Kuees U.,
RA   Lucas S., Van de Peer Y., Podila G.K., Polle A., Pukkila P.J.,
RA   Richardson P.M., Rouze P., Sanders I.R., Stajich J.E., Tunlid A.,
RA   Tuskan G., Grigoriev I.V.;
RT   "The genome of Laccaria bicolor provides insights into mycorrhizal
RT   symbiosis.";
RL   Nature 452:88-92(2008).
RN   [2]
RP   INDUCTION.
RX   PubMed=24942908; DOI=10.1186/1471-2164-15-492;
RA   Plaza D.F., Lin C.W., van der Velden N.S., Aebi M., Kuenzler M.;
RT   "Comparative transcriptomics of the model mushroom Coprinopsis cinerea
RT   reveals tissue-specific armories and a conserved circuitry for sexual
RT   development.";
RL   BMC Genomics 15:492-492(2014).
CC   -!- FUNCTION: Velvet-domain-containing protein that probably acts as a
CC       positive regulator of sexual development.
CC       {ECO:0000305|PubMed:24942908}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- INDUCTION: Expression is up-regulated during fruiting body formation
CC       (PubMed:24942908). {ECO:0000269|PubMed:24942908}.
CC   -!- SIMILARITY: Belongs to the velvet family. {ECO:0000305}.
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DR   EMBL; DS547097; EDR10330.1; -; Genomic_DNA.
DR   RefSeq; XP_001878780.1; XM_001878745.1.
DR   AlphaFoldDB; B0D4E7; -.
DR   SMR; B0D4E7; -.
DR   EnsemblFungi; EDR10330; EDR10330; LACBIDRAFT_317102.
DR   GeneID; 6074656; -.
DR   KEGG; lbc:LACBIDRAFT_317102; -.
DR   HOGENOM; CLU_044751_0_0_1; -.
DR   InParanoid; B0D4E7; -.
DR   OrthoDB; 1407766at2759; -.
DR   Proteomes; UP000001194; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.3960; -; 1.
DR   InterPro; IPR021740; Velvet.
DR   InterPro; IPR037525; Velvet_dom.
DR   InterPro; IPR038491; Velvet_dom_sf.
DR   PANTHER; PTHR33572; PTHR33572; 1.
DR   Pfam; PF11754; Velvet; 1.
DR   PROSITE; PS51821; VELVET; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Sporulation; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..345
FT                   /note="Probable velvet family sexual development regulator
FT                   LACBIDRAFT_317102"
FT                   /id="PRO_0000435923"
FT   DOMAIN          62..306
FT                   /note="Velvet"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01165"
FT   REGION          1..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          138..189
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          310..345
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        310..337
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   345 AA;  39099 MW;  ADC1ECEE18269281 CRC64;
     MFTTHPQGRS YRSSVPHHHL RQPEIQNSYD QHANNPPRQT RRRPLADMIG HPIHFLTGQF
     AGQTIRAELD EIQKADLGRK YARVDRRPLD PPPVVRLRYF DIREDDVDQE RGTEIKNYDE
     IQTIGLMSTV DLFPVPNESW TSRSPTQTSF SSSSPTLSNG NENFMFSSPQ TSSPTAAQSQ
     ASTPNSPSSN DIIHYVGNHA ITESSKVTSS LVGATFVQPA IVDYEGKKTI IFVFSDLAVK
     IEGTFLLRYR VFDIYSRPRD REDLLVQAEC YGGPFRVYST KEFPGLQAST DLTKHLARWG
     VRLNIRETER KRRKKGEIGS PLDDPKSKRK RTSLGSEDDE ASDED