ID   VEXB_SALTI              Reviewed;         264 AA.
AC   P43109;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 133.
DE   RecName: Full=Vi polysaccharide export inner-membrane protein VexB;
GN   Name=vexB; OrderedLocusNames=STY4654, t4347;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=GIFU 10007;
RX   PubMed=8331073; DOI=10.1128/jb.175.14.4456-4465.1993;
RA   Hashimoto Y., Li N., Yokoyama H., Ezaki T.;
RT   "Complete nucleotide sequence and molecular characterization of ViaB region
RT   encoding Vi antigen in Salmonella typhi.";
RL   J. Bacteriol. 175:4456-4465(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: May form an ATP-driven Vi polysaccharide export apparatus, in
CC       association with the VexA, VexC and VexD proteins.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ABC-2 integral membrane protein family.
CC       {ECO:0000305}.
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DR   EMBL; D14156; BAA03197.1; -; Genomic_DNA.
DR   EMBL; AL513382; CAD06774.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO71800.1; -; Genomic_DNA.
DR   PIR; G36892; G36892.
DR   RefSeq; NP_458733.1; NC_003198.1.
DR   RefSeq; WP_001023498.1; NZ_WSUR01000012.1.
DR   AlphaFoldDB; P43109; -.
DR   SMR; P43109; -.
DR   STRING; 220341.16505424; -.
DR   TCDB; 3.A.1.101.2; the atp-binding cassette (abc) superfamily.
DR   EnsemblBacteria; AAO71800; AAO71800; t4347.
DR   KEGG; stt:t4347; -.
DR   KEGG; sty:STY4654; -.
DR   PATRIC; fig|220341.7.peg.4753; -.
DR   eggNOG; COG1682; Bacteria.
DR   HOGENOM; CLU_060703_5_1_6; -.
DR   OMA; AFRQVQP; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0015774; P:polysaccharide transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR013525; ABC_2_trans.
DR   InterPro; IPR000412; ABC_2_transport.
DR   Pfam; PF01061; ABC2_membrane; 1.
DR   PRINTS; PR00164; ABC2TRNSPORT.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Polysaccharide transport;
KW   Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..264
FT                   /note="Vi polysaccharide export inner-membrane protein
FT                   VexB"
FT                   /id="PRO_0000182997"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        176..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        239..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          38..259
FT                   /note="ABC transmembrane type-2"
SQ   SEQUENCE   264 AA;  30429 MW;  0BA26D941CE7B9BE CRC64;
     MNILKNNSYY FMKLITVCEL IILLMSRDIK TRYNGNLLNY MMVLAVPLVW ISITVISFQY
     LNRSVPISTD DISFVIAGIL PYLLFRYTIT ATMRTHSFST SLAVVSQVKK RHVIFSLAAI
     EFVNAVIIYI IISLINFLIF SRWEAQKPFL IFEGMVIAWL LGLSFGYFCD ALSERFPLVY
     KAVPVMLRPM FLISAVFYTA NELPYSLLSI FSWNPLLHAN EIVREGMFEG YHSLYLEPFY
     PLAFSATLFL AGLIFHLICD TENH