ID   VEXIN_BOVIN             Reviewed;         203 AA.
AC   Q0VCV7;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Vexin {ECO:0000250|UniProtKB:Q8BG31};
GN   Name=VXN {ECO:0000250|UniProtKB:Q8BG31};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Brain cortex;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for neurogenesis in the neural plate and retina.
CC       Strongly cooperates with neural bHLH factors to promote neurogenesis.
CC       {ECO:0000250|UniProtKB:Q8BG31}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8BG31}.
CC       Nucleus {ECO:0000250|UniProtKB:Q8BG31}. Note=Nuclear localization is
CC       essential for its function in neurogenesis.
CC       {ECO:0000250|UniProtKB:Q8BG31}.
CC   -!- SIMILARITY: Belongs to the vexin family. {ECO:0000305}.
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DR   EMBL; BC119975; AAI19976.1; -; mRNA.
DR   RefSeq; NP_001069943.1; NM_001076475.1.
DR   AlphaFoldDB; Q0VCV7; -.
DR   STRING; 9913.ENSBTAP00000002838; -.
DR   PaxDb; Q0VCV7; -.
DR   Ensembl; ENSBTAT00000002838; ENSBTAP00000002838; ENSBTAG00000002192.
DR   GeneID; 617724; -.
DR   KEGG; bta:617724; -.
DR   CTD; 254778; -.
DR   VEuPathDB; HostDB:ENSBTAG00000002192; -.
DR   VGNC; VGNC:52627; VXN.
DR   eggNOG; ENOG502S3CJ; Eukaryota.
DR   GeneTree; ENSGT00390000010499; -.
DR   HOGENOM; CLU_116780_0_0_1; -.
DR   InParanoid; Q0VCV7; -.
DR   OMA; DRWDTGD; -.
DR   OrthoDB; 1228752at2759; -.
DR   TreeFam; TF336189; -.
DR   Proteomes; UP000009136; Chromosome 14.
DR   Bgee; ENSBTAG00000002192; Expressed in occipital lobe and 60 other tissues.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR   GO; GO:0022008; P:neurogenesis; ISS:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   InterPro; IPR040470; Vexin.
DR   InterPro; IPR027900; Vexin_dom.
DR   PANTHER; PTHR31520; PTHR31520; 1.
DR   Pfam; PF15505; DUF4648; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Neurogenesis; Nucleus; Reference proteome.
FT   CHAIN           1..203
FT                   /note="Vexin"
FT                   /id="PRO_0000271013"
FT   REGION          59..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   203 AA;  22246 MW;  FE080A5B76EA958D CRC64;
     MHQIYSCSDE NIEVFTTVIP SKVTSPARRR VKSSQHLLTK NVVIESDLYA PRPVELLPHR
     TDRRDGEGRW SGRFQNPRLQ GPHPAKTPAR PVGTSEPKSA NLCGNRTYGK ALMPPVARIS
     VKAPTVLEAA APGSENVAVL TRGSRHLKKM TEEFPTLPQG AEASLPLTGS APCGMPSILR
     KMWTRHKKKS EYVGATNSAF EAD