ID   VF108_ASFM2             Reviewed;         111 AA.
AC   Q65233;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=Inner membrane protein H108R {ECO:0000305};
DE            Short=pH108R;
GN   OrderedLocusNames=Mal-125; ORFNames=j5R;
OS   African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10500;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8409937; DOI=10.1099/0022-1317-74-10-2125;
RA   Vydelingum S., Baylis S.A., Bristow C., Smith G.L., Dixon L.K.;
RT   "Duplicated genes within the variable right end of the genome of a
RT   pathogenic isolate of African swine fever virus.";
RL   J. Gen. Virol. 74:2125-2130(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8021596; DOI=10.1099/0022-1317-75-7-1655;
RA   Dixon L.K., Twigg S.R.F., Baylis S.A., Vydelingum S., Bristow C.,
RA   Hammond J.M., Smith G.L.;
RT   "Nucleotide sequence of a 55 kbp region from the right end of the genome of
RT   a pathogenic African swine fever virus isolate (Malawi LIL20/1).";
RL   J. Gen. Virol. 75:1655-1684(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   CHARACTERIZATION, AND SUBCELLULAR LOCATION.
RX   PubMed=9603333; DOI=10.1099/0022-1317-79-5-1179;
RA   Brookes S.M., Sun H., Dixon L.K., Parkhouse R.M.E.;
RT   "Characterization of African swine fever virion proteins j5R and j13L:
RT   immuno-localization in virus particles and assembly sites.";
RL   J. Gen. Virol. 79:1179-1188(1998).
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000250|UniProtKB:Q65188};
CC       Single-pass membrane protein {ECO:0000305}. Note=Detected mainly on
CC       membrane-like structures within viral factories (PubMed:9603333).
CC       Probably part of the inner envelope (By similarity).
CC       {ECO:0000250|UniProtKB:Q65188, ECO:0000269|PubMed:9603333}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the asfivirus H108R family. {ECO:0000305}.
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DR   EMBL; X71982; CAA50825.1; -; Genomic_DNA.
DR   EMBL; AY261361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Proteomes; UP000000860; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Glycoprotein; Late protein; Membrane; Transmembrane; Transmembrane helix;
KW   Virion.
FT   CHAIN           1..111
FT                   /note="Inner membrane protein H108R"
FT                   /id="PRO_0000373472"
FT   TRANSMEM        10..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        65
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   111 AA;  12952 MW;  5D69FBB3257DBDFD CRC64;
     MVNLFPVFTL IVIITILITT RELSTTMLIV SLVTDYIIIN TQYTEQQHEM NTFSTQQLPQ
     KNSFNESYNK DKKSNTHIPY QWLAPELKEA ENKYWWGNYD PYSEPVLAGA S