VF146_ASFM2
ID VF146_ASFM2 Reviewed; 146 AA.
AC Q65240;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 2.
DT 03-AUG-2022, entry version 53.
DE RecName: Full=Uncharacterized protein E146L;
DE Short=pE146L;
GN OrderedLocusNames=Mal-137; ORFNames=j16L;
OS African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Asfuvirales; Asfarviridae; Asfivirus.
OX NCBI_TaxID=10500;
OH NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8021596; DOI=10.1099/0022-1317-75-7-1655;
RA Dixon L.K., Twigg S.R.F., Baylis S.A., Vydelingum S., Bristow C.,
RA Hammond J.M., Smith G.L.;
RT "Nucleotide sequence of a 55 kbp region from the right end of the genome of
RT a pathogenic African swine fever virus isolate (Malawi LIL20/1).";
RL J. Gen. Virol. 75:1655-1684(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Kutish G.F., Rock D.L.;
RT "African swine fever virus genomes.";
RL Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}. Virion {ECO:0000250|UniProtKB:Q65197}.
CC -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the asfivirus E146L family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA50836.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; X71982; CAA50836.1; ALT_FRAME; Genomic_DNA.
DR EMBL; AY261361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Proteomes; UP000000860; Genome.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Host membrane; Membrane; Transmembrane; Transmembrane helix; Virion.
FT CHAIN 1..146
FT /note="Uncharacterized protein E146L"
FT /id="PRO_0000373526"
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 107..109
FT /note="LNA -> ER (in Ref. 1; CAA50836)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 146 AA; 16080 MW; A0CED8C0B8FA1A5E CRC64;
MGGTTDFVLS ITIVLVILII IAFIWYNFTG WSPFKYSKGN TVTFKTPDES SIAYMRFKNC
VFTFTDPKGS LHSVDVTNVL NNMAKGFRDA QNPPSSFTLG GHCQAPLNAF SFILPGVNDR
ATVATADEAK KWENCDATLT GLQRII