ID   VF184_IIV3              Reviewed;         941 AA.
AC   Q196T9;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   03-AUG-2022, entry version 49.
DE   RecName: Full=Putative helicase 121R;
DE            EC=3.6.4.-;
GN   ORFNames=IIV3-121R;
OS   Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Pimascovirales; Iridoviridae; Betairidovirinae; Chloriridovirus.
OX   NCBI_TaxID=345201;
OH   NCBI_TaxID=7163; Aedes vexans (Inland floodwater mosquito) (Culex vexans).
OH   NCBI_TaxID=42431; Culex territans.
OH   NCBI_TaxID=332058; Culiseta annulata.
OH   NCBI_TaxID=310513; Ochlerotatus sollicitans (eastern saltmarsh mosquito).
OH   NCBI_TaxID=329105; Ochlerotatus taeniorhynchus (Black salt marsh mosquito) (Aedes taeniorhynchus).
OH   NCBI_TaxID=7183; Psorophora ferox.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16912294; DOI=10.1128/jvi.00464-06;
RA   Delhon G., Tulman E.R., Afonso C.L., Lu Z., Becnel J.J., Moser B.A.,
RA   Kutish G.F., Rock D.L.;
RT   "Genome of invertebrate iridescent virus type 3 (mosquito iridescent
RT   virus).";
RL   J. Virol. 80:8439-8449(2006).
CC   -!- SIMILARITY: Belongs to the IIV-6 184L family. {ECO:0000305}.
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DR   EMBL; DQ643392; ABF82151.1; -; Genomic_DNA.
DR   RefSeq; YP_654693.1; NC_008187.1.
DR   GeneID; 4156332; -.
DR   KEGG; vg:4156332; -.
DR   Proteomes; UP000001358; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016817; F:hydrolase activity, acting on acid anhydrides; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR014015; Helicase_SF3_DNA-vir.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014818; Phage/plasmid_primase_P4_C.
DR   InterPro; IPR014819; PriCT_2.
DR   Pfam; PF08706; D5_N; 1.
DR   Pfam; PF08707; PriCT_2; 1.
DR   SMART; SM00885; D5_N; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51206; SF3_HELICASE_1; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coiled coil; Helicase; Hydrolase; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..941
FT                   /note="Putative helicase 121R"
FT                   /id="PRO_0000378037"
FT   DOMAIN          609..791
FT                   /note="SF3 helicase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00551"
FT   REGION          492..514
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          285..323
FT                   /evidence="ECO:0000255"
FT   BINDING         653..660
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00551"
SQ   SEQUENCE   941 AA;  109757 MW;  F28969F6FA00268E CRC64;
     MNQLYSFFKN CNSFGAPPPL YTHVFLGSRP GKFYLSASSD NEFYTLYNSL VEAKTPVCVA
     EKQDDYVPLL GDVDLKVCID QENAFLKKTR VLYGEEELRA IVKCFQDTIK KNVVDWRDYH
     LICVALEKKP YMAGEYLKNG FHLHFPYLYL EKEKVKNVII PKIKEMVAAF RLGSGKRLFA
     DIDDAPENFI DDVTNKCWLM YGSSKSEDKK PYRISQVYSG NLEPMDLYEA FSIKPFYTKE
     EEPITVTVDN VKKILPQLLS ISSIKKEVLN VKTPMDLKIP TKIYLKQELK DIEGENSETI
     KRNLKDAKDL LKILNKKRAN EYNSWWDIGI ILFNIGHGCE DAFTIWDKWS SYSDKYDPDA
     CVQVWNSMHL RNPRFSKIKG MGSLRWYVKQ DNLKGYTAWV DKMHGLVLDE KNLVECVTRL
     EIMTTDTPLA RLMLDLYSGE YVFSDAGWYS FNGTIWSPVK VLKDFRVKFE HISTKYKEMR
     KRIMELIYHK NDDSGRDSEE DSQEEEVSSS QEQLSAKHRA ILMAKYRDIN RAINKLENFA
     TQNGILKMCE VFFYNEDFSD LLDENPLLIA FKNGVFDFET LTFRKGLQSD YLSKTLNIRY
     DDTLTDDSEE VLELYNFLSK IFPDEKVRAY FVDQICEVFR GGNRDKIAMF WTGNGNNGKS
     VTQRLFETMI GKKLAVKLST SVLTERIQPG QPNPQLTRLR GGIRWGVFDE WGKTEQILSG
     SLNVLTGGDS LPCRDLFQKG SDSSDFTPMF KLLCICNELP CLKDAVDATW DRIRIIPFES
     KFVAREKCPE TEQEQREKKL FLCDTEITQK DRMESLARAL GWYLVKIFKE KEKKRRNGTY
     QVTIPDKVND AKLKYQAKCD ILAFFMEETY LKTDNQDHKI PFDDMYISFK NWYINSFSGK
     MVTLNKHEFI EMVRNKYNLT ETDKALRGYM WNRNYDDSDD E