ID   VF421_ASFB7             Reviewed;         421 AA.
AC   Q07384;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 52.
DE   RecName: Full=Uncharacterized protein K421R;
DE            Short=pK421R;
GN   OrderedLocusNames=Ba71V-052; ORFNames=K421R;
OS   African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10498;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8506138; DOI=10.1093/nar/21.10.2423;
RA   Yanez R.J., Boursnell M.E., Nogal M.L., Yuste L., Vinuela E.;
RT   "African swine fever virus encodes two genes which share significant
RT   homology with the two largest subunits of DNA-dependent RNA polymerases.";
RL   Nucleic Acids Res. 21:2423-2427(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA   Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA   Rodriguez J.F., Vinuela E.;
RT   "Analysis of the complete nucleotide sequence of African swine fever
RT   virus.";
RL   Virology 208:249-278(1995).
RN   [3]
RP   SUBCELLULAR LOCATION.
RX   PubMed=30185597; DOI=10.1128/jvi.01293-18;
RA   Alejo A., Matamoros T., Guerra M., Andres G.;
RT   "A Proteomic Atlas of the African Swine Fever Virus Particle.";
RL   J. Virol. 92:0-0(2018).
RN   [4]
RP   INDUCTION.
RX   PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA   Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA   Dixon L., Werner F.;
RT   "The African Swine Fever Virus Transcriptome.";
RL   J. Virol. 94:0-0(2020).
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:30185597}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       {ECO:0000269|PubMed:32075923}.
CC   -!- SIMILARITY: Belongs to the asfivirus K421R family. {ECO:0000305}.
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DR   EMBL; Z21490; CAA79700.1; -; Genomic_DNA.
DR   EMBL; U18466; AAA65282.1; -; Genomic_DNA.
DR   PIR; S33998; S33998.
DR   RefSeq; NP_042746.1; NC_001659.2.
DR   GeneID; 22220434; -.
DR   KEGG; vg:22220434; -.
DR   Proteomes; UP000000624; Genome.
PE   2: Evidence at transcript level;
KW   Late protein; Reference proteome; Virion.
FT   CHAIN           1..421
FT                   /note="Uncharacterized protein K421R"
FT                   /id="PRO_0000221953"
SQ   SEQUENCE   421 AA;  49411 MW;  EDD9A7DAC23BC3A8 CRC64;
     MYTHVDVVGI AEASAALYVQ KDRDRYLDVL TTIENFIYQH KCIITGESAH LLFLKKNIYL
     YEFYSNNVAE HSKALATLLY KLDPEYLTRY TVLITKIPNH WYVINVDQRE FVRLYAIPAV
     KQHLPIPILP FYCTSALTHQ ELFCLGPELQ LIQIYSKLCN PNFVEEWPTL LDYEKSMRML
     FLEQFPRRLE IAGGKKEEEK HESIIKKIIL EMVSTRQRIV VGGYIQKNLY NHVLKNRNRL
     QLITSLDIYE EKDIIQQFCD SNGLKIKIRI NNPLLPTNPE LRRLTIYFNH NNDDDQSYLI
     VDMYNTGSYE LVPTNQINTL DGSFLIGTPF VQARFLLVEI WVLMLIAQQT KKDTKKIIQF
     FINQYEMLMN SPWPSMEALF PSSSKRYLGN YVDPNALIKW AQLKLKRIPP FYPGKPDEES
     C