ID   VF602_ASFB7             Reviewed;         602 AA.
AC   Q65169;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 60.
DE   RecName: Full=Protein B602L;
DE            Short=pB602L;
GN   OrderedLocusNames=Ba71V-079; ORFNames=B602L;
OS   African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10498;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA   Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA   Rodriguez J.F., Vinuela E.;
RT   "Analysis of the complete nucleotide sequence of African swine fever
RT   virus.";
RL   Virology 208:249-278(1995).
RN   [2]
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=17035321; DOI=10.1128/jvi.01323-06;
RA   Epifano C., Krijnse-Locker J., Salas M.L., Rodriguez J.M., Salas J.;
RT   "The African swine fever virus nonstructural protein pB602L is required for
RT   formation of the icosahedral capsid of the virus particle.";
RL   J. Virol. 80:12260-12270(2006).
RN   [3]
RP   FUNCTION.
RX   PubMed=31530894; DOI=10.1038/s41422-019-0232-x;
RA   Liu Q., Ma B., Qian N., Zhang F., Tan X., Lei J., Xiang Y.;
RT   "Structure of the African swine fever virus major capsid protein p72.";
RL   Cell Res. 29:953-955(2019).
RN   [4]
RP   INDUCTION.
RX   PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA   Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA   Dixon L., Werner F.;
RT   "The African Swine Fever Virus Transcriptome.";
RL   J. Virol. 94:0-0(2020).
CC   -!- FUNCTION: Plays an essential role in the assembly of the icosahedral
CC       capsid of the virus (PubMed:17035321, PubMed:31530894). Allows the
CC       assembly of 3 molecules of hexon protein p72 and formation of a
CC       thermostable trimer (PubMed:31530894). {ECO:0000269|PubMed:17035321,
CC       ECO:0000269|PubMed:31530894}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000269|PubMed:17035321}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       {ECO:0000269|PubMed:32075923}.
CC   -!- SIMILARITY: Belongs to the asfivirus B602L family. {ECO:0000305}.
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DR   EMBL; U18466; AAA65309.1; -; Genomic_DNA.
DR   RefSeq; NP_042773.1; NC_001659.2.
DR   GeneID; 22220309; -.
DR   KEGG; vg:22220309; -.
DR   Proteomes; UP000000624; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Host cytoplasm; Late protein; Reference proteome; Repeat.
FT   CHAIN           1..602
FT                   /note="Protein B602L"
FT                   /id="PRO_0000373700"
FT   REPEAT          161..164
FT                   /note="1"
FT   REPEAT          165..168
FT                   /note="2"
FT   REPEAT          169..172
FT                   /note="3"
FT   REPEAT          173..176
FT                   /note="4"
FT   REPEAT          177..180
FT                   /note="5"
FT   REPEAT          181..184
FT                   /note="6"
FT   REPEAT          185..188
FT                   /note="7"
FT   REPEAT          189..192
FT                   /note="8"
FT   REPEAT          193..196
FT                   /note="9"
FT   REPEAT          197..200
FT                   /note="10"
FT   REPEAT          201..204
FT                   /note="11"
FT   REPEAT          205..208
FT                   /note="12"
FT   REPEAT          209..212
FT                   /note="13"
FT   REPEAT          213..216
FT                   /note="14"
FT   REPEAT          217..220
FT                   /note="15"
FT   REPEAT          221..224
FT                   /note="16"
FT   REPEAT          225..228
FT                   /note="17"
FT   REPEAT          229..232
FT                   /note="18"
FT   REPEAT          233..236
FT                   /note="19"
FT   REPEAT          237..240
FT                   /note="20"
FT   REPEAT          241..244
FT                   /note="21"
FT   REPEAT          245..248
FT                   /note="22"
FT   REPEAT          249..252
FT                   /note="23"
FT   REPEAT          253..256
FT                   /note="24"
FT   REPEAT          257..260
FT                   /note="25"
FT   REPEAT          261..264
FT                   /note="26"
FT   REPEAT          265..268
FT                   /note="27"
FT   REPEAT          269..272
FT                   /note="28"
FT   REGION          161..272
FT                   /note="28 X 4 AA tandem repeats of [CNG]-[AV]-[DNS]-[MT]"
SQ   SEQUENCE   602 AA;  68017 MW;  2C90A95DBD3F6D9D CRC64;
     MAEFNIDELL KNVLEDPSTE ISEETLKQLY QRTNPYKQFK NDSRVAFCSF TNLREQYIRR
     LIMTSFIGYV FKALQEWMPS YSKPTHTTKT LLSELITLVD TLKQETNDVP SESVVNTILS
     IADSCKTQTQ KSKEAKTTID SFLREHFVFD PNLHAQSAYT CASTCADTNV DTCASTCAST
     CASTCASTCA STCASTCAST GASTCADTNV DTCASTCADT NVDTCASTCA DTNVDTCAST
     CADTNVNTCA SMCADTNVDT CASTCANTCA STEYTDLADP ERIPLHIMQK TLNVPNELQA
     DIDAITQTPQ GYRAAAHILQ NIELHQSIKH MLENPRAFKP ILFNTKITRY LSQHIPPQDT
     FYKWNYYIED NYEELRAATE SIYPEKPDLE FAFIIYDVVD SSNQQKVDEF YYKYKDQIFS
     EVSSIQLGNW TLLGSFKANR ERYNYFNQNN EIIKRILDRH EEDLKIGKEI LRNTIYHKKA
     KNIQETGPDA PGLSIYNSTF HTDSGIKGLL SFKELKNLEK ASGNIKKARE YDFIDDCEEK
     IKQLLSKENL TPDEESELIK TKKQLNNALE MLNVPDDTIR VDMWVNNNNK LEKEILYTKA
     EL